# ZEISS LSM 980 plus AIRYSCAN 2 for NYMC Imaging Core

> **NIH NIH S10** · NEW YORK MEDICAL COLLEGE · 2020 · $594,269

## Abstract

PROJECT SUMMARY
New York Medical College is dedicated to building biomedical research at the College. A key part of the
College Strategic Plan is improving the Core Research Facilities that are most needed by researchers for
their current and future research projects. The proposed LSM 980 plus Airyscan 2 system integrated in
into the College Histological Laboratory and Imaging Core will meet a tremendous unmet need for
investigators for state of the art high resolution imaging of both live and fixed cells including
Fluorescence Energy Transfer (FRET) Microscopy and Fluorescence Recovery After Photobleaching
(FRAP) Microscopy. The Research of many of the Major and Minor Users at NYMC involve thicker
tissue sections for which a high resolution confocal with high sensitivity as provided by the Airyscan 2 is
essential. Currently there is not a high-resolution confocal system at NYMC or to our knowledge between
NYC and Albany NY available to NYMC investigators or other federally funded investigators in the
region. The proposal includes 8 highly projective Major Users and more than 8 Minor Users that span
more than four major disciplines at NYMC; all have identified a critical need for a high resolution confocal
for fixed cell and/or live cell imaging for their studies. The user group includes basic science and clinical
investigators that span cardiovascular research, metabolic disorders, infectious diseases, neurology,
neonatology, microbiology, microbiome, dental health, immunology and cancer. It also supports NYMC
translational science institutes in Cardiovascular Disease and Child Health and research groups in
Vector-borne Diseases and Neurobiological Disorders. Major and Minor NIH funded Users comprise over
90% of the estimated AUT for the instrument. Thus the proposed LSM 980 plus Airyscan 2 meets a
critical unmet need for NIH funded investigators at NYMC for their active research programs. It will also
allow these investigators to open new innovative lines of inquire and research proposals that require
more advanced imaging capabilities than are currently available to investigators at NYMC.
The previous generation LSM 880 with Fast Airyscan is one of the most scientifically cited systems for
core imaging facilities due to its high resolution, high sensitivity, and gentle low toxicity imaging of
processes in life cells. All Major/Minor Users have agreed that the new Zeiss LSM 980 plus Airyscan 2
will best fit the current/future needs of investigators for high resolution confocal imaging of both live and
fixed cells. Due to its flexibility and its ability to readily be upgraded in the field, it is also excellent for core
imaging facilities that have to meet the needs of a diverse group of biomedical investigators.

## Key facts

- **NIH application ID:** 9939022
- **Project number:** 1S10OD028527-01
- **Recipient organization:** NEW YORK MEDICAL COLLEGE
- **Principal Investigator:** DANA G MORDUE
- **Activity code:** S10 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $594,269
- **Award type:** 1
- **Project period:** 2020-08-15 → 2021-08-14

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9939022

## Citation

> US National Institutes of Health, RePORTER application 9939022, ZEISS LSM 980 plus AIRYSCAN 2 for NYMC Imaging Core (1S10OD028527-01). Retrieved via AI Analytics 2026-05-31 from https://api.ai-analytics.org/grant/nih/9939022. Licensed CC0.

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