# Illumina NovaSeq 6000 Sequencing System

> **NIH NIH S10** · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · 2020 · $583,334

## Abstract

PROJECT SUMMARY/ABSTRACT
We are applying for matching funding to purchase a second Illumina NovaSeq 6000 sequencing system to
handle increased sequencing needs from NIH-funded projects at the University of California at San Francisco
(UCSF). Our current NovaSeq is approaching capacity and we will not be able to accommodate projects that
are ramping up. The NovaSeq will be placed in the UCSF Center for Advanced Technology (CAT) core facility.
The CAT is the only high throughput core facility at UCSF dedicated on research projects. The CAT was
founded almost 20 years ago and has had a rich history of providing access and services to genomics
technologies, starting with microarrays and transitioning to next-generation sequencing (NGS) over a decade
ago starting with the original Solexa 1G sequencer to the Illumina NovaSeq.
At UCSF, 36 labs in 21 departments have utilized the NovaSeq. We have also provided support for labs and
core facilities at sister UC campuses such as UC Berkeley, UC Davis, UC Irvine, UC Riverside, and UC San
Diego. The projects and applications span the gamut and include cancer genomics and epigenomics,
metagenomic sequencing, functional genomics, single cell sequencing, massively parallel reporter assays,
autoimmunity, and HIV/ADIS work.
UCSF researchers have been pioneers in the development and deployment of genomic methods such as
ribosome profiling, CRISPRa/i screens, and many types of single-cell sequencing methods. The CAT and its
sequencing services have been integral to this work. Besides running the sequencing systems, the highly
trained CAT staff provides deep domain knowledge that accelerates the progress of science and projects at
UCSF and beyond.

## Key facts

- **NIH application ID:** 9939104
- **Project number:** 1S10OD028511-01
- **Recipient organization:** UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
- **Principal Investigator:** ERIC D CHOW
- **Activity code:** S10 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $583,334
- **Award type:** 1
- **Project period:** 2020-06-01 → 2022-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9939104

## Citation

> US National Institutes of Health, RePORTER application 9939104, Illumina NovaSeq 6000 Sequencing System (1S10OD028511-01). Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/grant/nih/9939104. Licensed CC0.

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