# An AVANCE NEO 400 MHz NMR Spectrometer for Chemical Biology and Drug Discovery

> **NIH NIH S10** · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · 2020 · $599,000

## Abstract

PROJECT SUMMARY
NMR spectroscopy is a highly versatile and powerful biophysics method vital for structural and chemical
analysis of small-molecule chemical compounds. Funding is sought to support acquisition of a state-of-the-
art Bruker AVANCE NEO 400 MHz NMR spectrometer at the Icahn School of Medicine at Mount Sinai. The
proposed NMR spectrometer system will be configured with a high performance AVANCE NEO console and
equipped with a high-sensitivity X-nuclei-optimized double resonance broad banded Cryo-probe ProdigyTM
and an automatic NMR sample changer (SampleCase). This new NMR system will be available to all
investigators at the Icahn School of Medicine at Mount Sinai, and will greatly enhance the essential NMR
spectroscopy needs for NIH-funded chemical biology and drug discovery research projects by major users
in their pursuit of discovery of fundamental molecular mechanisms of biology and development of new
treatments for human diseases.

## Key facts

- **NIH application ID:** 9939195
- **Project number:** 1S10OD028504-01
- **Recipient organization:** ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
- **Principal Investigator:** Ming-Ming Zhou
- **Activity code:** S10 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $599,000
- **Award type:** 1
- **Project period:** 2020-06-01 → 2021-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9939195

## Citation

> US National Institutes of Health, RePORTER application 9939195, An AVANCE NEO 400 MHz NMR Spectrometer for Chemical Biology and Drug Discovery (1S10OD028504-01). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/9939195. Licensed CC0.

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