# Imaging Core

> **NIH NIH P01** · YALE UNIVERSITY · 2020 · $103,638

## Abstract

Abstract/Summary: Core B will continue to serve the role it plays in our present PPG, while introducing two
novel CT imaging components for phenotyping embryonic arteriogenesis in mice and assessing permeability in
the setting of hindlimb ischemia in adult mice. All three projects extensively utilize Doppler flow velocity system
for blood flow measurements and high-resolution microCT imaging for arteriogenesis phenotyping, with
molecular, cellular and sub-organelle studies. For embryonic phenotyping, the Core will perform primary
services necessary for the desired imaging procedures such as catheterization and en bloc staining. The Core
will execute high-resolution microCT image acquisition, reconstruction, and analysis. These standardized
efforts will result in optimal image acquisition and processing, reduce variability and maximize data reliability,
while facilitating the translation of ideas from the bench to mice, and ultimately to humans. Core B procedures
will be performed by two research specialists under the direction of Dr. Zhenwu Zhuang.

## Key facts

- **NIH application ID:** 9939654
- **Project number:** 5P01HL107205-08
- **Recipient organization:** YALE UNIVERSITY
- **Principal Investigator:** Zhenwu Zhuang
- **Activity code:** P01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $103,638
- **Award type:** 5
- **Project period:** — → —

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9939654

## Citation

> US National Institutes of Health, RePORTER application 9939654, Imaging Core (5P01HL107205-08). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/9939654. Licensed CC0.

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