# QE-HF-X Mass Spectrometer

> **NIH NIH S10** · UNIVERSITY OF CALIFORNIA AT DAVIS · 2020 · $600,000

## Abstract

Project Summary/Abstract
We request funds for a Thermo Fisher Scientific Q Exactive HF-X mass spectrometer and nano
UPLC to be housed in the Proteomics Core of the UC Davis Genome Center. The Proteomics
Core facility is the sole resource in the area and performs a large number of proteomic analyses.
However, the needs of many researchers in the areas of quantitative proteomics are currently not
being met with existing instrumentation. The Thermo Scientific Q Exactive HF-X is a next-
generation state-of-the-art mass spectrometer that has several unique characteristics that will
enable the proteomics core to perform additional quantitative proteomics profiling experiments
such as Data Independent Analysis (DIA). The Q Exactive HF-X is expected to have an
immediate and a significant impact on the research efforts of the major users listed in this
proposal and the greater UC Davis research community and the nascent biotechnology start-ups
clustered in the area. This LC-MS system will be integrated into our Proteomics Core facility
which has been operating successfully since 2005. The Proteomics Core’s existing infrastructure
will oversee the operation, maintenance, and management of this instrument. Additionally, the
UC Davis Genome Center and the UC Davis Central Campus will support the additional funds
needed for this instrument demonstrating UC Davis’s continued commitment for proteomics and
the successful housing and efficient utilization of NIH funded instrumentation.

## Key facts

- **NIH application ID:** 9940104
- **Project number:** 1S10OD026918-01A1
- **Recipient organization:** UNIVERSITY OF CALIFORNIA AT DAVIS
- **Principal Investigator:** Brett S Phinney
- **Activity code:** S10 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $600,000
- **Award type:** 1
- **Project period:** 2020-09-10 → 2021-09-09

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9940104

## Citation

> US National Institutes of Health, RePORTER application 9940104, QE-HF-X Mass Spectrometer (1S10OD026918-01A1). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/9940104. Licensed CC0.

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