# Acquisition of an Eiger2 X 16M pixel array detector for macromolecular crystallography

> **NIH NIH S10** · NORTHWESTERN UNIVERSITY · 2020 · $2,000,000

## Abstract

A group of researchers requests funds to purchase an Eiger2 X 16M state-of-
the-art pixel array detector for synchrotron-based macromolecular crystallography. All
the researchers are members of the user community of the Life Sciences Collaborative
Access Team (LS-CAT) at the Advanced Photon Source (APS), a third generation
synchrotron source that will soon be upgraded to the next generation source. The new
detector will form part of LS-CAT and will expand its capabilities significantly. The new
Eiger2 X 16M detector is optimized for the brightest synchrotrons and ensure optimal
use of the very bright x-ray beam after the upcoming APS upgrade. The detector is a
versatile instrument that will help accomplish two major goals: a) better data quality due
to the higher dynamic range of the Eiger2 detector, and 2) adoption of better data
collection strategies optimized for challenging problems. The proposed instrument is
ideally suited for the research purposes of the user community and will ensure that the
user community at LS-CAT remains at the forefront of modern approaches to the study
of biological macromolecules. In addition, the new detector will be available to the larger
structural biology community as LS-CAT devotes 25% of the available time to outside
users. The major and minor users comprise several active and productive laboratories
with well-supported research programs that will benefit immediately from the proposed
detector.

## Key facts

- **NIH application ID:** 9940366
- **Project number:** 1S10OD028680-01
- **Recipient organization:** NORTHWESTERN UNIVERSITY
- **Principal Investigator:** Alfonso Mondragon
- **Activity code:** S10 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $2,000,000
- **Award type:** 1
- **Project period:** 2020-08-15 → 2022-08-14

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9940366

## Citation

> US National Institutes of Health, RePORTER application 9940366, Acquisition of an Eiger2 X 16M pixel array detector for macromolecular crystallography (1S10OD028680-01). Retrieved via AI Analytics 2026-05-21 from https://api.ai-analytics.org/grant/nih/9940366. Licensed CC0.

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