# Upgrade of the RF electronics console and probes for chemical biology.

> **NIH NIH S10** · WEILL MEDICAL COLL OF CORNELL UNIV · 2020 · $600,000

## Abstract

7. Project Summary
This proposal requests funds to acquire a modern console and autosampler for an existing
600MHz NMR magnet to support chemical biology at Weill Cornell Medicine. The instrument will
directly support 8 NIH funded investigators. The NMR console and autosampler requested will
replace an outdated 20 year-old Varian electronics and provide a modern probe and console to
better meet the demands for NMR instrument time. This instrumentation will provide new
capabilities to Weil Cornell Medicine including: broad-band detection which includes 19F(564MHz)
31P(243MHz)-to-199Hg(107MHz) and 17O(81.4MHz)- to- 109Ag(27.8MHz); a significantly expanded
experimental temperature range available for data collection and automation features that will
simplify data collection and expand the potential NMR user base. This instrumentation will
positively impact basic and translational NIH funded research, enhancing the NMR resources
needed for medicinal chemistry, chemical biology and molecular targeting. The funded research
supported by this instrumentation has relevance to cancer, neural growth/repair, bone
growth/repair, amyloid pathogenesis and male birth control.

## Key facts

- **NIH application ID:** 9940379
- **Project number:** 1S10OD028556-01
- **Recipient organization:** WEILL MEDICAL COLL OF CORNELL UNIV
- **Principal Investigator:** WILLIAM CLAY BRACKEN
- **Activity code:** S10 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $600,000
- **Award type:** 1
- **Project period:** 2020-07-01 → 2022-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9940379

## Citation

> US National Institutes of Health, RePORTER application 9940379, Upgrade of the RF electronics console and probes for chemical biology. (1S10OD028556-01). Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/grant/nih/9940379. Licensed CC0.

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