# Significant upgrade and expansion of the Southwest National Primate Research Center Pathology Unit

> **NIH NIH S10** · TEXAS BIOMEDICAL RESEARCH INSTITUTE · 2020 · $489,000

## Abstract

Abstract
The Southwest National Primate Research Center (SNPRC) is one of the seven NIH-supported
national primate resources in the country. Since its inception as an NPRC in 1999, the SNPRC
has been a productive member of the NPRC consortium and has supported research nation-wide.
Currently the SNPRC supports the research of 50+ core and affiliate faculty scientists with a >$
130 million foot-print of the currently funded grants, most of which are through the NIH. These
include multiple R01 grants, as well as programmatic initiatives (P01, U19, UH3 etc.).
The central mission of the SNPRC is to improve the health of our global community through
innovative biomedical research and to serve as a national resource for biomedical research
involving nonhuman primates. The SNPRC achieves this mission by providing nonhuman
primates for animal research, scientific expertise, and specialized facilities and equipment to
investigators doing groundbreaking research. To effectively maintain a research-oriented
nonhuman primate colony of this magnitude, a strong presence of veterinary diagnostic resources
including clinicians, pathologists, medical technologists, veterinary technicians, and a well-
equipped diagnostic core laboratory is required. The anatomic and clinical pathology core
laboratories at SNPRC are therefore integral to the central mission of SNPRC. Through the
analyses of body fluids, tissues (histopathology), and molecular pathology techniques such as
immunohistochemistry, in-situ hybridization, and stereology, pathology core labs facilitate better
understanding of disease pathogenesis and provide novel insights into the mechanistic details of
the disease progression.
The instrumentation central for the daily functioning of the Pathology Unit are however, extremely
old, outdated and not supported by the manufacturer’s for software, updates and support. In order
to meet the high-volume load, short turnaround time, and complicated demands of a large
research colony of approximately 3,000 nonhuman primates, access to cutting edge equipment
is absolutely critical. The clinical pathology laboratory utilizes an 11 yr old Beckman UniCel DxC
600 fully automated blood chemistry analyzer. This workhorse accounts for about 75% of the
clinical pathology procedures per year. In has reached the end of its serviceable lifespan.
Similarly, the automated slide stainer and the coverslipper are considered to be the workhorse for
the anatomic pathology lab. However, both are extremely outdated and at the end of the life.
This application seeks to outfit the Pathology Unit of the SNPRC with a new chemistry analyzer,
a new slide stainer and coverslipper, as well as seeks to purchase a state-of-the-art whole slide
scanner, which will provide significant upgrade to the research capabilities supported by the
SNPRC.

## Key facts

- **NIH application ID:** 9940621
- **Project number:** 1S10OD028732-01
- **Recipient organization:** TEXAS BIOMEDICAL RESEARCH INSTITUTE
- **Principal Investigator:** Deepak Kaushal
- **Activity code:** S10 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $489,000
- **Award type:** 1
- **Project period:** 2020-09-02 → 2021-09-01

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9940621

## Citation

> US National Institutes of Health, RePORTER application 9940621, Significant upgrade and expansion of the Southwest National Primate Research Center Pathology Unit (1S10OD028732-01). Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/grant/nih/9940621. Licensed CC0.

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