# University of Pittsburgh Clinical and Translational Science Institute

> **NIH NIH UL1** · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · 2020 · $15,166,493

## Abstract

Contact PD/PI: REIS, STEVEN E
In 2006, we created the University of Pittsburgh Clinical and Translational Science Institute (CTSI) as the
academic home for clinical and translational science in western Pennsylvania. We revolutionized the practice of
translational research at Pitt and at our partnering institution, the University of Pittsburgh Medical Center
(UPMC), by training 850 translational scientists, incorporating team science in the promotions and tenure
process, supporting 2225 investigators and 4049 research studies, and forging a collaborative research
environment. We created and led the SPIRiT Consortium (6 CTSA hubs) and the NCATS Accrual to Clinical
Trials network (21 CTSA hubs). Published manuscripts from a broad range of translational research studies
that directly benefitted from CTSI support have been cited >81,000 times in the literature. Over the next 5
years, we will apply our infrastructure, training programs, best practices, and novel approaches to support
translational science and scientists and to advance each of the national CTSA goals through our Overall Aims:
1) Workforce Development: Enhance and expand our diverse and team-oriented translational science
workforce by providing them with the specialized skills, knowledge, and core competencies required to advance
translation of their discoveries through innovative education methods, experiential training, and continuous
learning opportunities; 2) Collaboration and Engagement: Engage an inclusive group of stakeholders as
partners in the full translational research process and enable their contributions as members of teams
conducting collaborative research; 3) Integration: Integrate into research programs those populations that
have been traditionally excluded or studied in isolation and support and enhance studies that span the lifespan
and translational research spectrum; 4) Methods/Processes: Promote innovation, quality, and efficiency across
the translational research spectrum by developing and disseminating new research methodologies; adopting
best practices from CTSA hubs, industry, and sectors outside of translational science; facilitating project
management; and streamlining institutional research processes, with an emphasis on multi-center clinical
trials; and 5) Informatics: Infuse informatics tools and methodologies across the research life cycle and
translational research spectrum, efficiently integrate research and clinical data in a secure research data
repository, and enable secure data sharing locally and nationally. In addition to the 7 required Components and
our rigorous KL2 and TL1 training programs, we will expand our range and breadth of accomplishments
through two Optional Components that leverage great strengths and opportunities in Innovation as a
Discipline and Biomedical Modeling. Thus, the impact of CTSI, with its exceptional institutional support and
committed and enthusiastic team, will continue to be significant, locally, regionally, and nati...

## Key facts

- **NIH application ID:** 9941163
- **Project number:** 5UL1TR001857-05
- **Recipient organization:** UNIVERSITY OF PITTSBURGH AT PITTSBURGH
- **Principal Investigator:** STEVEN E REIS
- **Activity code:** UL1 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $15,166,493
- **Award type:** 5
- **Project period:** 2016-07-12 → 2021-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9941163

## Citation

> US National Institutes of Health, RePORTER application 9941163, University of Pittsburgh Clinical and Translational Science Institute (5UL1TR001857-05). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/9941163. Licensed CC0.

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