# BSL3 Core

> **NIH NIH P01** · JOHNS HOPKINS UNIVERSITY · 2020 · $280,597

## Abstract

BSL-3 CORE - ABSTRACT
The overall hypothesis for this PPG application is that both resting CD4+ T cells and resident macrophages
harbor latent SIV genomes during longterm antiretroviral therapy (ART), and therefore contribute to the
rebound of virus in blood, CSF, and tissues after ART cessation.
The BSL-3 Core is a pivotal part of this proposal since all four research projects will utilize samples collected
from infected macaques. To support this overall PPG, we will:
A) Quickly execute targeted measures data for each project and communicate it rapidly to investigators;
consult and communicate daily with team members of all of the individual projects to provide support on
sample preparation, quantitation of biological parameters, and data dissemination;
B) Work hand in hand with the Animal Core to isolate the appropriate samples and prepare them in a manner
for subsequent analysis with the appropriate methods;
C) Continually update project specific and overall databases and provide coherent data summaries and figures
suitable for inclusion into manuscripts to facilitate data dissemination and communication;
D) Provide access to cutting edge technologies to support projects and identify and apply technologies to
streamline analysis and increase productivity and data quality.

## Key facts

- **NIH application ID:** 9947879
- **Project number:** 5P01AI131306-04
- **Recipient organization:** JOHNS HOPKINS UNIVERSITY
- **Principal Investigator:** Lucio Gama
- **Activity code:** P01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $280,597
- **Award type:** 5
- **Project period:** — → —

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9947879

## Citation

> US National Institutes of Health, RePORTER application 9947879, BSL3 Core (5P01AI131306-04). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/9947879. Licensed CC0.

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