# Understanding and Addressing Vaccination Disparities Among Rural Adolescents

> **NIH ALLCDC U01** · UNIVERSITY OF COLORADO DENVER · 2020 · $350,000

## Abstract

PROJECT SUMMARY/ABSTRACT
At a national level, vaccination rates among rural adolescents are significantly lower than that of urban
adolescents for human papillomavirus (HPV) and meningococcal (MenACWY) vaccines. This disparity leaves
millions of rural adolescents unprotected against the diseases these vaccines prevent. In rural Western
Colorado, HPV and MenACWY levels are 20%-50% lower than in urban locations, and a similar pattern is also
seen for the tetanus-diphtheria-acellular pertussis (Tdap) vaccine. Improving rural adolescent vaccination rates
is thus a public health priority for the state. Little is known about why these urban/rural disparities in vaccination
exist, or how to mitigate them. The specific objectives of this application are to address these knowledge
gaps by 1) using a mixed-methods approach to understand the reasons underlying this disparity from the
parent and provider perspective, and by 2) using a community-engaged research process, called Boot Camp
Translation (BCT), to design and test community-relevant strategies to mitigate this disparity among rural
Colorado adolescents BCT is a 6-month iterative, community engagement process that involves educating
community stakeholders to become local experts in a topic of interest, guiding them through a series of steps
to help them develop a set of messages, promotional products and implementation plans to achieve a health
goal, and helping them then take these plans and products back to their communities to be implemented. BCT
has proven efficacy for increasing compliance with a variety recommended health behaviors in rural Colorado.
Preliminary data indicate the process is likely to be similarly effective for vaccination. The efficacy of using
BCT to develop successful vaccine-promoting strategies will be assessed using a cluster, randomized,
controlled trial in which 8 communities in rural Western Colorado will undergo Boot Camp Translation (BCT),
and 8 will not. Adolescent vaccination rates will be compared between the two study arms. To achieve our
project goals, we propose the following Aims:
 1) Assess reasons underlying disparities in vaccination among rural adolescents
 2) Use Boot Camp Translation (BCT) to develop community-relevant strategies to increase
 adolescent vaccination
 3) Evaluate the impact of the BCT-designed strategies on rural adolescent vaccination rates.
A strength of using the BCT approach for developing vaccination promoting strategies is that such strategies
are dissemination-ready, can incorporate individual, practice and community context, and can have improved
acceptability to individual communities. We believe that these facets will help us achieve the overarching goal
of this project - to develop a replicable approach for increasing adolescent vaccine uptake that can be
adaptable and feasible to use in rural settings more broadly.

## Key facts

- **NIH application ID:** 9948524
- **Project number:** 5U01IP001091-03
- **Recipient organization:** UNIVERSITY OF COLORADO DENVER
- **Principal Investigator:** Amanda F Dempsey
- **Activity code:** U01 (R01, R21, SBIR, etc.)
- **Funding institute:** ALLCDC
- **Fiscal year:** 2020
- **Award amount:** $350,000
- **Award type:** 5
- **Project period:** 2018-09-01 → 2021-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9948524

## Citation

> US National Institutes of Health, RePORTER application 9948524, Understanding and Addressing Vaccination Disparities Among Rural Adolescents (5U01IP001091-03). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/9948524. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*
