# Precision in Symptom Self-Management (PriSSM) Center

> **NIH NIH P30** · COLUMBIA UNIVERSITY HEALTH SCIENCES · 2020 · $537,053

## Abstract

PROJECT SUMMARY: OVERALL
Latinos are the fastest growing ethnic group in the United States comprising almost half of the immigrant
population and by 2060 are estimated to represent 29% of the total population. Although often treated as a
homogeneous population, Latinos vary in culture as well as in genetic ancestry admixture. The former may
influence symptom experience and responses as well as self-management needs. The latter influences
disease risk and treatment responses, and Ancestry Informative Markers have been developed to quantify
admixture for Latinos in the Americas. However, little is known about how these cultural and genetic factors
interact in the context of symptom science. The goal of the Precision in Symptom Self-Management (PriSSM)
Center is to advance the science of symptom self-management for Latinos through a social ecological lens that
takes into account variability in individual, interpersonal, organizational, and environmental factors across the
life course. The aims of the PriSSM Center are to:
 1. Develop sustainable interdisciplinary, biobehavioral research capacity for symptom self-management
 research by establishing a sociotechnical infrastructure including centralized research resources,
 2. Enable symptom self-management feasibility research that will develop into new programs of research
 and independent investigator research applications by supporting six pilot projects,
 3. Advance symptom self-management for Latinos through synergistic research activities informed by a
 social ecological lens and precision medicine approaches, and
 4. Assess the PriSSM Center activities, impact, and sustainability through formative and summative
evaluation.
To achieve the aims of the PriSSM Center, the Administrative and Pilot Projects Cores are complemented by a
Precision Medicine Core. This aligns with the National Institutes of Health Symptom Science Model and its four
components: 1) complex symptom or cluster identification, 2) phenotypic characterization, 3) biomarker
discovery, and 4) clinical application. The Columbia University School of Nursing has a robust research base of
symptom self-management studies. There are multiple areas of innovation within the PriSSM Center: use of
the Social Ecological Model as the theoretical underpinning for the Center, application of data science
methods, and the integration of Ancestry Informative Markers and genetic findings related to common and rare
conditions as common data elements in all pilot projects. The PriSSM Center will use the exceptional
institutional resources and the proposed research activities to reduce the knowledge gap related to the science
of symptom self-management for Latinos of diverse heritage.

## Key facts

- **NIH application ID:** 9951129
- **Project number:** 5P30NR016587-05
- **Recipient organization:** COLUMBIA UNIVERSITY HEALTH SCIENCES
- **Principal Investigator:** SUZANNE BAKKEN
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $537,053
- **Award type:** 5
- **Project period:** 2016-08-16 → 2022-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9951129

## Citation

> US National Institutes of Health, RePORTER application 9951129, Precision in Symptom Self-Management (PriSSM) Center (5P30NR016587-05). Retrieved via AI Analytics 2026-05-29 from https://api.ai-analytics.org/grant/nih/9951129. Licensed CC0.

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