# Training in Trauma and Sepsis Research

> **NIH NIH T32** · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · 2020 · $519,091

## Abstract

Trauma and sepsis are among the most important causes of morbidity and mortality in humans. The Pitt
Trauma Research Training Program (Pitt TRTP) is focused on the training of physician-scientists and
talented full-time PhDs in trauma, sepsis, and related pathobiological process including ischemia/reperfusion
injury and wound healing. Progress in complex clinical fields such as trauma and sepsis requires investigative
teams collectively possessing skills in diverse areas of research. These specialized research areas include,
systems and computational biology, bench/translational research, and health services research, and thus
require scientists capable of managing and evaluating large clinical data sets, other scientists facile with in
silico simulations and computational strategies, other investigators skilled in reverse translating clinical
observations into relevant preclinical models (both small and large animals), and finally, investigators well-
versed in the design and execution of clinical trials in acutely ill trauma/surgical patients. To address these
inter- and multidisciplinary needs, we have organized the Pitt TRTP around three core tracks: 1) the Surgical
Outcomes, Health Services and Policy (SOHSP) Track; 2) The Systems Biology Track; and 3) the
Bench/Translational Research Track. A Director with demonstrated expertise oversees each track, which in
turn consists of expert faculty fully engaged with the program. These investigators have worked together for
many years in collaborative, multidisciplinary teams. The Pitt TRTP leverages extensive local resources at the
University of Pittsburgh School of Medicine, including robust clinical and research programs in trauma, acute
care surgery, Surgical Critical Care, and sepsis research; world-class clinical programs (from which the patient
data and biobanks are procured), including three Level Trauma Centers which admit over 8,000 trauma and
4000 acute care surgery patients per year as well as carrying out multiple clinical trials in the setting of trauma
and sepsis; collaborating departments with international expertise in computational and systems biology along
with immunology; and extensive core facilities which support current- and next-generation “omics” research.

## Key facts

- **NIH application ID:** 9952371
- **Project number:** 5T32GM008516-27
- **Recipient organization:** UNIVERSITY OF PITTSBURGH AT PITTSBURGH
- **Principal Investigator:** TIMOTHY R BILLIAR
- **Activity code:** T32 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $519,091
- **Award type:** 5
- **Project period:** 1994-07-01 → 2024-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9952371

## Citation

> US National Institutes of Health, RePORTER application 9952371, Training in Trauma and Sepsis Research (5T32GM008516-27). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/9952371. Licensed CC0.

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