# Component A: Wisconsin Study to Explore Early Development of Autism (SEED)

> **NIH ALLCDC U01** · UNIVERSITY OF WISCONSIN-MADISON · 2020 · $770,377

## Abstract

Abstract
This proposal is to establish a recruitment, data collection and collaborative research site in Wisconsin for the
multi-site Study to Explore Early Development (SEED) of autism spectrum disorder (ASD) of the Center for
Disease Control and Prevention (CDC). The overall goals of the SEED are to: characterize phenotypic
variability and identify relatively homogeneous subgroups of ASD; and investigate risk factors for ASD by
comparing the early exposures and development of well-characterized ASD cases and controls selected to
represent diverse population subgroups. The specific aims of this project are to: (1) implement the SEED 3
protocol in a 20-county catchment area (4,015 births in 2014) in south and central Wisconsin that
encompasses the Wisconsin Autism and Developmental Disabilities Monitoring (ADDM) Network catchment
area where surveillance of ASD and other developmental disabilities as part of CDC's ADDM Network has
been underway since surveillance year 2002; (2) to enhance recruitment and achieve enrollment and data
collection targets for 375 children and their pares, as specified in the SEED 3 protocol; (3) submit data and
biospecimens collected according to the SEED 3 protocol to the Centers for Autism and Developmental
Disability Research Epidemiology (CADDRE) Data Coordinating Center and SEED Central Laboratory and
Biosample Repository, respectively; and (4) collaborate with other CADDRED members and actively
participate in relevant CADDRE workgroups, data analysis and preparation of manuscripts, including at least
five manuscripts to be led by the Wisconsin SEED research team. This research will generate new knowledge
of the risk factors for and potential prevention of ASD, a leading category of disability among children, with
effects across the lifespan.

## Key facts

- **NIH application ID:** 9953914
- **Project number:** 5U01DD001215-05
- **Recipient organization:** UNIVERSITY OF WISCONSIN-MADISON
- **Principal Investigator:** Maureen S Durkin
- **Activity code:** U01 (R01, R21, SBIR, etc.)
- **Funding institute:** ALLCDC
- **Fiscal year:** 2020
- **Award amount:** $770,377
- **Award type:** 5
- **Project period:** 2016-07-01 → 2021-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9953914

## Citation

> US National Institutes of Health, RePORTER application 9953914, Component A: Wisconsin Study to Explore Early Development of Autism (SEED) (5U01DD001215-05). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/9953914. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*