# Analysis Core

> **NIH NIH P30** · COLUMBIA UNIVERSITY HEALTH SCIENCES · 2020 · $114,639

## Abstract

ANALYSIS CORE SUMMARY
There is extensive need for development of a skilled workforce for the study of disparities in Alzheimer’s Disease
and Related Dementias (ADRD). Due to the aging of the US population, the numbers of persons with ADRD are
increasing. The exponential rise of numbers of people with ADRD is greater among ethnic minorities, particularly
Hispanics and non-Hispanic Blacks, compared with Non-Hispanic Whites. The study of health disparities related
to ADRD requires a transdisciplinary approach that includes research in social determinants of health (SDOH),
behavioral science, mental health, epidemiology, ADRD biomarkers, neuropsychology, measurement,
biostatistics, bioinformatics, clinical trials, and caregiving. The Columbia Center for Interdisciplinary Research on
Alzheimer's Disease Disparities (CIRAD) Analysis Core (AnC) has three main goals: 1) assist in the production
and application of new measures and methods for studying health, social and environmental factors, and
behavior across the life course among ethnically diverse populations; 2) provide technical assistance to RCMAR
Scientists; and 3) support a mentoring method for pilot investigators through study grids to be used in the Work-
in-Progress (WIP) mentoring seminars, methods internships and training workshops. CIRAD will work with the
other RCMAR AnCs and the Coordinating Center (CC) in: a) collaborative research projects, b) publications, and
c) a website resource that contains measurement reviews and recommendations for appropriate measures and
methods for use in studying ADRD in diverse populations. The AnC will leverage collaborations with the
Alzheimer’s Disease Research Centers (ADRC) at Columbia University Medical Center (CUMC), the Pepper
Center at Mt. Sinai School of Medicine and the Weill Cornell Roybal Center to provide cross-site research and
mentoring opportunities for RCMAR Scientists. The AnC will assist Research Education Component (REC)
leaders (Drs. Luchsinger and Manly) with applications from RCMAR Scientists. A focus of methodological
development will be related to the primary theme of the CIRAD: interdisciplinary research on biological,
behavioral, sociocultural, and environmental mechanisms of disparities in Alzheimer's disease and related
dementias (ADRD), including risk and resilience factors, biomarkers, and caregiving. The proposed AnC is
focused on measurement, but is also examining analytic methods for secondary data analyses involving
biomarkers.The AnC will achieve its goals through the following specific aims: Specific Aim 1: Measurement:
Identifying, cataloging, and distributing culturally informed measures; Specific Aim 2: Methodological and
statistical mentoring; Specific Aim 3: Development of methods and analyses related to the CIRAD theme of
mechanisms of ADRD disparities; Specific Aim 4: Development of new lines of investigation (using existing and
secondary data).

## Key facts

- **NIH application ID:** 9961477
- **Project number:** 5P30AG059303-03
- **Recipient organization:** COLUMBIA UNIVERSITY HEALTH SCIENCES
- **Principal Investigator:** Jeanne A. Teresi
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $114,639
- **Award type:** 5
- **Project period:** 2018-09-01 → 2023-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9961477

## Citation

> US National Institutes of Health, RePORTER application 9961477, Analysis Core (5P30AG059303-03). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/9961477. Licensed CC0.

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