# Neuromotor Mechanisms and Rehabilitation

> **NIH NIH P30** · UNIVERSITY OF MARYLAND BALTIMORE · 2020 · $258,394

## Abstract

7. Project Summary- Resource Core 3
The central hypothesis of the Neuromotor Mechanisms and Rehabilitation (NMR) Core (Resource Core-3) is
that appropriately-selected activity and exercise-based rehabilitation interventions can promote beneficial
changes in brain ((central nervous system (CNS) structure, connectivity, and physiology)) and neuromotor
mechanisms to improve motor performance and function and minimize disability in chronic medical conditions
affecting older people. Resource Core-3 (RC-3) provides support, guidance, and mentoring to UM-OAIC
investigators using a multi-system approach focused on whole-body balance, mobility, and upper limb activities
to address the mechanistic bases upon which to build novel rehabilitation strategies to improve motor function
and independence and promote recovery in older people with chronic disease-associated disabilities. Through
this framework, functional activity and exercise-mediated brain and neuromotor plasticity can be identified to
guide condition-specific and individual-specific rehabilitation approaches for minimizing disability. The
complementary and collaborative relationship between RC-3 and RC-2 focusing on muscle, metabolic, and
cardiovascular mechanisms of aging with disability, forges a strong and comprehensive inter-core synergy for
understanding the multi-system bases for designing and testing effective new rehabilitation programs. RC-3
collaborates across UM-OAIC cores in research working groups to train and develop the next generation of
investigators and rehabilitation interventions that will enhance motor function in older adults with chronic
disability. Using a toolbox of methodologies, it performs quantitative tests of whole-body posture and balance,
mobility, upper limb activities, and functional tasks that characterize the processes of brain and neuromotor
control and plasticity underlying functional activity and exercise derived gains in motor performance and
function across UM-OAIC interventions.
RC-3 will continue to support, augment, and develop ongoing and new projects that will define the changes in
both the CNS and the periphery with chronic disabling conditions of aging, and devise effective rehabilitation
programs to enhance motor function and prevent chronic disability.

## Key facts

- **NIH application ID:** 9962227
- **Project number:** 5P30AG028747-15
- **Recipient organization:** UNIVERSITY OF MARYLAND BALTIMORE
- **Principal Investigator:** MARK W ROGERS
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $258,394
- **Award type:** 5
- **Project period:** — → —

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9962227

## Citation

> US National Institutes of Health, RePORTER application 9962227, Neuromotor Mechanisms and Rehabilitation (5P30AG028747-15). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/9962227. Licensed CC0.

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