# 3D Tissue Imaging

> **NIH NIH P30** · INDIANA UNIVERSITY INDIANAPOLIS · 2020 · $188,912

## Abstract

Recent developments in optical sectioning microscope systems have provided biomedical researchers
with the capability to conduct high-resolution, high-content 3D microscopy at the scale of millimeters, if not
centimeters in biological tissues. Image volumes of this size and complexity are enormously rich in potential
information. However, microscopy at this scale introduces new sets of challenges with respect to data
handling, image visualization and quantitative analysis that limit the ability of most researchers to realize this
potential. The overarching goal of the 3-dimensional Tissue Imaging (3DTI) core is to make large-scale,
quantitative 3D microscopy accessible and productive for renal researchers, regardless of their institutional
infrastructure or their expertise in imaging.
 Service of the 3DTI core will consist of two components. First, the core will provide imaging services,
which will consist of preparing a sample for fluorescence microscopy, collecting high-resolution image volumes
by confocal microscopy, and combining these image volumes into a single hyper-volume. Second, the core
will provide access, training and support to investigators in the use of a high-performance image analysis
system that can be used by remote investigators in a client-server format. Taking advantage of the advanced
computer and networking infrastructure of Indiana University, this system will be designed to provide remote
investigators with a powerful, yet easy-to-use tool for interactive exploration and analysis of their image data.

## Key facts

- **NIH application ID:** 9963206
- **Project number:** 5P30DK079312-14
- **Recipient organization:** INDIANA UNIVERSITY INDIANAPOLIS
- **Principal Investigator:** Tarek Maurice Ashkar
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $188,912
- **Award type:** 5
- **Project period:** — → —

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9963206

## Citation

> US National Institutes of Health, RePORTER application 9963206, 3D Tissue Imaging (5P30DK079312-14). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/9963206. Licensed CC0.

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