# Molecular Biology Core

> **NIH NIH P20** · OKLAHOMA STATE UNIVERSITY STILLWATER · 2020 · $174,145

## Abstract

PROJECT SUMMARY
 All the Phase II CoBRE projects utilize molecular biology approaches to understand the molecular
mechanisms of respiratory diseases caused by respiratory pathogens, including influenza virus (Project 1 and
Project 2), Streptococcus pneumoniae (Project 3) and Pseudomonas aeruginosa (Project 4). The overall
objective of the Molecular Biology Core (MBC) is to provide centralized services and technical expertise in
molecular biology for Phase II CoBRE project investigators, pilot project investigators, and other investigators.
The specific aims of the MBC are to provide services and support for 1) functional studies using RNAi and
CRISPR/Cas9, transgene overexpression, and mutagenesis/deletion, 2) genome-wide gene profiling using
RNA sequencing, 3) molecular assays including reporter assays and real-time quantitative PCR, 4) reagents
for respiratory and infectious disease research including primary lung cells, respiratory viruses and bacteria,
and 5) advice, consultation and training on various aspects of molecular biology and developing or adopting
new methods as needed.

## Key facts

- **NIH application ID:** 9963267
- **Project number:** 5P20GM103648-08
- **Recipient organization:** OKLAHOMA STATE UNIVERSITY STILLWATER
- **Principal Investigator:** LIN LIU
- **Activity code:** P20 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $174,145
- **Award type:** 5
- **Project period:** — → —

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9963267

## Citation

> US National Institutes of Health, RePORTER application 9963267, Molecular Biology Core (5P20GM103648-08). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/9963267. Licensed CC0.

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