# Integrative Training in Oncogenic Signaling

> **NIH NIH T32** · MEDICAL UNIVERSITY OF SOUTH CAROLINA · 2020 · $361,325

## Abstract

PROJECT SUMMARY/ABSTRACT
This proposal seeks National Cancer Institute (NCI) support for an exciting new Integrative Training in
Oncogenic Signaling (ITOS) Program that has been developed by a select group of cancer scientists affiliated
with the Hollings Cancer Center (HCC) at the Medical University of South Carolina (MUSC). The ITOS
Program takes place in this active and growing medical center environment with state-of-the-art facilities, a
vibrant NCI-designated cancer center, and an active Office of Postdoctoral Affairs. Led by a Program Director
with an exceptionally strong cancer research background and leadership experience, the ITOS Program will
select and support the placement of trainees in experienced, well-funded, productive laboratories led by the
Program Faculty who reside in an interactive, multi-departmental research environment with extensive
resources. Each trainee will have a primary mentor and one or two secondary mentors with complementary
expertise to ensure distinct and valuable perspectives that will enhance the overall cancer-related research
training experience. The objectives of this training program are to provide proactive mentoring and oversight
and research training in cutting-edge methodology; to develop useful academic and essential career
development skills; to foster collaborative, interdisciplinary interactions with faculty and other trainees; and to
provide exposure to current cancer research discoveries and how these are being translated into novel
approaches to prevention, diagnosis, and treatment of cancer.
Slated to train five postdoctoral trainees each year for five years, this robust training opportunity has seven
programmatic components essential in obtaining the aforementioned objectives. These include the following
components: 1) 33 Program Faculty who share common interests in cancer research and will provide the
essential mentoring for trainees; 2) one to two year experiences in Program Faculty laboratories found within
the vibrant HCC research environment; 3) an ITOS Program Research Club providing an engaging community
forum for the trainees and Program Faculty to discuss work in progress as well as the latest discoveries in
cancer science; 4) shared research resource workshops and tailored training with experts in cutting-edge
biotechnologies; 5) interdisciplinary engagement with trainees in HCC-sponsored thematic research retreats,
symposia, work in progress meetings, and seminars; 6) career development workshops and courses that will
equip trainees for independent success; and 7) opportunities to network nationally at a minimum of two
professional conferences each year. In summary, the ITOS Program will offer distinct experiences and
opportunities only afforded to the selected ITOS Fellows, and the program, led by an outstanding cadre of
Program Faculty, is anticipated to be highly attractive to emerging junior investigators locally and nationally.

## Key facts

- **NIH application ID:** 9964685
- **Project number:** 5T32CA193201-05
- **Recipient organization:** MEDICAL UNIVERSITY OF SOUTH CAROLINA
- **Principal Investigator:** Philip H Howe
- **Activity code:** T32 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $361,325
- **Award type:** 5
- **Project period:** 2016-07-08 → 2021-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9964685

## Citation

> US National Institutes of Health, RePORTER application 9964685, Integrative Training in Oncogenic Signaling (5T32CA193201-05). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/9964685. Licensed CC0.

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