# Quantifying Recovery of Muscle Strength after Exercise in Large Animal Model of Ischemic Myopathy from Peripheral Arterial Disease (PAD)

> **NIH VA I21** · VETERANS HEALTH ADMINISTRATION · 2020 · —

## Abstract

Peripheral arterial disease is a significant medical condition affecting aged members of our society, and it
disproportionately affects Veterans. Peripheral arterial disease deprives muscles in the legs of oxygen leading
to muscle injury and leg pain. Exercise therapy may improve muscle strength and function. We have
established an inter-disciplinary research team with expertise in vascular surgery, vascular biology, skeletal
muscle physiology, imaging, and large animal modeling of disease. In this proposal we will use this expertise to
develop and test isolated hindlimb muscle group strength in our large animal model of ischemic myopathy.

## Key facts

- **NIH application ID:** 9966783
- **Project number:** 5I21RX003188-02
- **Recipient organization:** VETERANS HEALTH ADMINISTRATION
- **Principal Investigator:** LUKE Packard BREWSTER
- **Activity code:** I21 (R01, R21, SBIR, etc.)
- **Funding institute:** VA
- **Fiscal year:** 2020
- **Award amount:** —
- **Award type:** 5
- **Project period:** 2019-07-01 → 2021-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9966783

## Citation

> US National Institutes of Health, RePORTER application 9966783, Quantifying Recovery of Muscle Strength after Exercise in Large Animal Model of Ischemic Myopathy from Peripheral Arterial Disease (PAD) (5I21RX003188-02). Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/grant/nih/9966783. Licensed CC0.

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