# Enhanced Surveillance for Newly Preventable Diseases (ARI and AGE Surveillance) - Rochester, NY

> **NIH ALLCDC U01** · UNIVERSITY OF ROCHESTER · 2020 · $1,505,484

## Abstract

ABSTRACT
 This proposal is to enhance the New Vaccine Surveillance Network (NVSN) site in Rochester, NY, which
has for 10 years been focused on prospective, population-based surveillance for acute gastroenteritis (AGE)
caused by rotavirus, norovirus, and other viral pathogens, and for the past year, population-based
surveillance for acute respiratory infections. We propose to continue and extend surveillance for ARI with a
focus on influenza, respiratory syncytial virus (RSV), enterovirus-D68 (EV-D68), and other vaccine-
preventable or potentially vaccine-preventable viruses, in order to both measure influenza vaccine
effectiveness (VE) in preventing laboratory-confirmed influenza infections among hospitalized children <18
years of age, and to assess the inpatient burden of viral pathogens associated with ARIs, particularly
influenza, RSV and EV-D68. We also will continue the AGE surveillance to allow for similar determinations of
AGE burden and rotavirus vaccine efficacy among children hospitalized or visiting the emergency
departments.
 The over-arching goal of the NVSN is to inform the nation about the burden of vaccine-preventable
diseases (VPDs), and the impact of new vaccines and vaccine policies. Our Rochester NVSN site (a founding
NVSN member), has been a leader in shaping all aspects of the NVSN, including population-based
surveillance for new or upcoming vaccines, vaccine effectiveness (VE) studies, refinement of diagnostic
laboratory methods, health services and epidemiologic studies, and dissemination of findings. We have the
infrastructure and comprehensive expertise to begin all activities on day 1 of the funding period.
 Our NVSN site has: experienced personnel who have led and published many past NVSN influenza VE,
surveillance, and molecular diagnostic laboratory studies; accurate laboratory and surveillance techniques
consistent with CDC procedures; and outstanding epidemiologic and health services research capabilities.
We have full access to all hospital and ED databases to complement surveillance activities. Our catchment
area, the Monroe County NY/Rochester Metropolitan Statistical Area, has a total population of >1,000,000;
>95% of ARI admissions for Monroe County resident children <18 years of age occur at our two NVSN
hospitals, with nearly 1,000 hospitalizations for ARIs per year. Thus, we have a “captured population”
precisely suited for the NVSN population-based surveillance projects. This proposal will provide critical
information to develop sound polices consistent with national goals to preventing VPD in children.

## Key facts

- **NIH application ID:** 9966823
- **Project number:** 5U01IP001049-05
- **Recipient organization:** UNIVERSITY OF ROCHESTER
- **Principal Investigator:** Geoffrey Alan Weinberg
- **Activity code:** U01 (R01, R21, SBIR, etc.)
- **Funding institute:** ALLCDC
- **Fiscal year:** 2020
- **Award amount:** $1,505,484
- **Award type:** 5
- **Project period:** 2016-09-01 → 2021-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9966823

## Citation

> US National Institutes of Health, RePORTER application 9966823, Enhanced Surveillance for Newly Preventable Diseases (ARI and AGE Surveillance) - Rochester, NY (5U01IP001049-05). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/9966823. Licensed CC0.

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