# TR&D4: Integrated pipeline for data analysis

> **NIH NIH P41** · NEW YORK STRUCTURAL BIOLOGY CENTER · 2020 · $132,269

## Abstract

TR&D4 - Integrated pipeline for data analysis
Summary
Computer programs are essential to the practice of modern NMR spectroscopy, because the quantity
of data and the sophistication of the requisite numerical analyses simply cannot be treated without
application of efficient and high-speed software. This situation, which applies across all of biological
NMR spectroscopy, is particularly critical in applications to conformational dynamics of biological
macromolecules because the underlying physical processes are highly complex and the NMR data
under the best of circumstances cannot fully capture such complexities. In such an under-determined
situation, careful data quantification, model-building, statistical analysis, and cross-validation are
essential to generation of robust results. Existing software for analysis of spin relaxation and other
NMR data for such investigations largely has been written for expert users by experts in the NMR
techniques (but not necessarily expert computer scientists) and is largely piecemeal. For effective
promulgation of the experimental technological research and developments at the Center on
Macromolecular Dynamics by NMR Spectroscopy (CoMD/NMR) to the broader scientific community,
modern, integrated, user-friendly software programs and data analysis pipelines are essential. TR&D4
will develop the necessary software in a feedback cycle with the other TR&D and DBP components,
building on the pioneering efforts of the lead investigators for this TR&D.

## Key facts

- **NIH application ID:** 9967028
- **Project number:** 5P41GM118302-04
- **Recipient organization:** NEW YORK STRUCTURAL BIOLOGY CENTER
- **Principal Investigator:** ARTHUR G PALMER
- **Activity code:** P41 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $132,269
- **Award type:** 5
- **Project period:** — → —

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9967028

## Citation

> US National Institutes of Health, RePORTER application 9967028, TR&D4: Integrated pipeline for data analysis (5P41GM118302-04). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/9967028. Licensed CC0.

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