# Analytical Biochemistry Shared Resource

> **NIH NIH P30** · UNIVERSITY OF HAWAII AT MANOA · 2020 · $163,328

## Abstract

ABSTRACT
 The Analytical Biochemistry Shared Resource (ABSR) facility has been providing cost-effective and
accurate chemical analyses for molecules relevant to cancer research to UHCC investigators since 1990. ABSR
has also served as the base for consultation related to analyte quantitation and strategies in analytical chemistry
in addition to providing services and expertise in advanced methods for the determination of biomarkers,
metabolites, or any organic chemicals using a state-of-the-art analytical chemistry approach including high
performance liquid chromatography (HPLC) with mass spectrometry (MS), photo-diode array (PDA),
electrochemical (EC), fluorescence (F), and other highly sensitive detectors. ABSR has established routine
clinical chemistry and single/multiplexed immunoassays including those utilizing Luminex technology for cost-
effective analyses. A host of new assays has also been implemented in the current cycle due to the rising needs
of CC members. The high quality of services is continually monitored by ABSR’s participation in internal and
external quality assurance programs such as the round robin tests organized by the National Institute of
Standards and Technology. ABSR provides state-of-the-art analytical chemistry services, which include
developing methods for simultaneous analyses of multiple analytes across various analytical platforms (LCMS,
HPLC, ELISA, clinical autoanalyzer). In addition, ABSR provides timely feedback on all project, providing the
most cost-efficient strategies as possible, and stimulating inter-disciplinary collaborations within the CC and other
institutions. No other laboratories in the State of Hawaii are available to provide this array of services particularly
regarding the type, speed, cost, and combination of assays, many of which are custom designed by this core to
fulfill the specific requirements of CC projects. The current use of the ABSR facility at full capacity is anticipated
to continue for the foreseeable future. Newly funded projects requiring services of the resource will outnumber
projects terminating in the coming years. Equipment obtained in the current cycle (high-resolution accurate-mass
spectrometry system) has greatly enhanced the capabilities of this resource. In FY12-17 this facility has shown
remarkable productivity by a total of 59 cancer related peer reviewed publications that involved services for
UHCC investigators by ABSR (33 inter-programmatic, 24 intra-programmatic) and contributed significantly to
scientific findings as detailed in the Research Strategy.

## Key facts

- **NIH application ID:** 9968041
- **Project number:** 5P30CA071789-20
- **Recipient organization:** UNIVERSITY OF HAWAII AT MANOA
- **Principal Investigator:** Adrian A Franke
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $163,328
- **Award type:** 5
- **Project period:** — → 2023-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9968041

## Citation

> US National Institutes of Health, RePORTER application 9968041, Analytical Biochemistry Shared Resource (5P30CA071789-20). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/9968041. Licensed CC0.

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