# Pediatric and Developmental Pharmacology for Inflammatory and Infectious Diseases

> **NIH NIH P50** · UNIVERSITY OF CALIFORNIA, SAN DIEGO · 2020 · $221,408

## Abstract

Administrative Core Abstract
The Administrative Core supports the program entitled “Pediatric and Developmental Pharmacology for
Inflammatory and Infectious Diseases” as a Specialized Center in Research in Pediatric Developmental
Pharmacology (RPDP) Program (U54) at UC San Diego. The goal of the Administrative Core is to make
certain that the entire UC San Diego RPDP program functions as efficiently and optimally as possible via the
following aims. In Aim 1, the Core will promote communication and overall cohesiveness among the various
elements of the UC San Diego RPDP Center to ensure efficient operations. To that end, the Administrative
Core will focus on organizing its group meetings, retreats, and journal clubs, and by addressing and solving
any and all institutional issues that arise. In Aim 2, the Core will track the financial status of the UC San Diego
RPDP Center and coordinate report generations for the IRB, FDA and NIH. In Aim 3 the Core will provide
ongoing critical evaluation and outcomes assessment to achieve continual improvement of RPDP
effectiveness by organizing independent external as well as internal reviews of the program. The Scientific
Advisory Committee will serve a key role as its members evaluate the RPDP Center and lend their expertise to
promote scientific progress. In Aim 4 the Core will promote the integration of cross-disciplinary research and
will serve as point of contact for outside entities seeking to collaborate with the RPDP, including the NICHD,
other NICHD-supported Pediatric Pharmacology Training (T32) Programs, other RPDP Centers and industry.
Through Aim 5 the Core will coordinate the pilot project application process and monitor project execution and
outcomes. With Aim 6 the Administrative Core will support the quantitative pharmacokinetic and
pharmacodynamics (PK/PD) modeling needs of the Projects and provide timely, accurate, and cost effective
quantitative assays in support of the analytical needs of the Projects through the establishment of a Clinical
Pharmacology Section under the leadership of Dr. Edmund Capparelli, a leader in the field of pediatric
PK/PD modeling. Through Aim 7 the Administrative Core will seek to continue the excellent track record of the
UC San Diego RPDP in training pediatric clinical pharmacologists through a Training and Outreach Section,
lead by Dr. Adriana Tremoulet, co-PI of a recently awarded NICHD-funded T32 in Clinical Pharmacology. This
Training and Outreach Section will provide an integrated educational and practical mentored research training
experience in pediatric clinical pharmacology for health sciences professionals interested in becoming leaders
in the field. This will serve as the platform for cross-training across the RPDP Centers as well. Efficient
organization, administration and communication is essential for overall RPDP Center success especially given
the translational nature of the research. Our success over the last five years as an RPDP Center demonst...

## Key facts

- **NIH application ID:** 9970235
- **Project number:** 5P50HD090259-05
- **Recipient organization:** UNIVERSITY OF CALIFORNIA, SAN DIEGO
- **Principal Investigator:** ADRIANA H TREMOULET
- **Activity code:** P50 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $221,408
- **Award type:** 5
- **Project period:** 2016-09-20 → 2021-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9970235

## Citation

> US National Institutes of Health, RePORTER application 9970235, Pediatric and Developmental Pharmacology for Inflammatory and Infectious Diseases (5P50HD090259-05). Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/grant/nih/9970235. Licensed CC0.

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