# Pathology of Mouse Models of Human Disease

> **NIH NIH R13** · JACKSON LABORATORY · 2020 · $20,000

## Abstract

PROJECT SUMMARY/ABSTRACT
The laboratory mouse is the premier animal model for studying human disease. Yet creation of mouse models
is outpacing the professional development and training of pathologists prepared to interpret the tissue
abnormalities that arise in mice experimentally manipulated, genetically engineered, within long-term aging
studies, or that develop spontaneous diseases. We propose to continue the annual Workshop on the
Pathology of Mouse Models for Human Disease to provide intense, interactive, training sessions aimed at the
next generation of veterinary and physician pathologists. A productive core group of organizing pathologists
will gather a rotating group of pathology specialists and research scientists, with 20% new presenters each
year, to deliver annual, 5 day long workshops each October from 2019-2021. The Jackson Laboratory (JAX) in
Bar Harbor, Maine will host the workshops; JAX continues to be a unique institution with a strong focus on the
genetics, biology, and pathology of laboratory mice. Workshop topics cover a range of diseases, not just
neoplastic, from those associated with aging to embryonic developmental abnormalities. Specific organ
systems will include, skin, bones, eyes, intestinal tract, pulmonary system, etc. Training will include
presentations on emerging technologies for creating genetically engineered mice, database resources
facilitating analyses and pathological cases studies contributed by participants and organizers. Participation
will remain ~25 to maximize interactions between the faculty and attendees, thereby encouraging networking
and collaboration. Our long-term objective is to develop a highly skilled cadre of comparative pathologists
capable of interpreting mouse lesions and applying this knowledge to research and training programs at their
respective institutions throughout the United States and beyond. We will also carry out a plan to have
appropriate representation of traditionally underrepresented individuals as workshop participants, using well-
established mechanisms at JAX and offering partial scholarships. Our innovative and comprehensive
workshop will offer a critical, unique training experience that is best delivered at JAX.

## Key facts

- **NIH application ID:** 9970565
- **Project number:** 5R13OD010920-19
- **Recipient organization:** JACKSON LABORATORY
- **Principal Investigator:** JOHN Paul SUNDBERG
- **Activity code:** R13 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $20,000
- **Award type:** 5
- **Project period:** 2002-07-25 → 2022-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9970565

## Citation

> US National Institutes of Health, RePORTER application 9970565, Pathology of Mouse Models of Human Disease (5R13OD010920-19). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/9970565. Licensed CC0.

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