# Duke Claude D. Pepper Older Americans Independence Center

> **NIH NIH P30** · DUKE UNIVERSITY · 2020 · $1,078,245

## Abstract

PROJECT SUMMARY/ABSTRACT - Overall
The Duke University Claude D. Pepper Older Americans Independence Center (Duke OAIC) will
provide intellectual leadership, innovation, interdisciplinary research strategies, translational
approaches, development of early investigators and a collaborative spirit in its theme: to
understand and optimize physiologic reserve and physical resilience in older adults. The specific
aims of the Duke OAIC are to support an integrated research program in our theme; to develop
and evaluate new methods that advance the field of reserve and resilience; to develop the next
generation of researchers who will become leaders in aging research related to the our theme;
and to support pilot studies that lead to more definitive research studies related to our theme.
The Duke OAIC has an experienced Leadership and Administrative Core in place that will direct
OAIC activities. The Duke OAIC supports a Research Education Component (REC),
Pilot/Exploratory Studies Core (PESC) and three resource cores: Molecular Measures Core,
Physical Measures Core, and Analysis Core. The resource cores provide collaborative support
to several externally funded projects, development projects, REC Scholars and PESC pilot
studies. In addition, the Molecular Measures Core will develop new molecular profiling and
systems pathway analyses to evaluate cellular, tissue and organ resiliencies and identify
resilient phenotypes. The Physical Measures Core will develop innovative measurement
approaches to resilience at the person level and support an annual Health Innovations
Technology competition. The Analysis Core will develop and disseminate new biostatistical
analytic methodologies to advance the study of resilience. The REC will coordinate delivery of
an aging research curriculum to early investigators across the University through a network
called the Duke Community of Scholars in conjunction with the Duke Clinical and Translational
Science Award (CTSA) and provide a structure for individualized aging research mentorship.
The PESC will facilitate the highest caliber pilot studies related to our theme. The Duke OAIC
will use several innovative mechanisms to facilitate career development and enhancement of
research capabilities, including the Data Integration Working Group, Research Colloquia on
Reserve and Resilience, Pepper Scholars Program, Intervention Development for Elderly Adults
(IDEA) workshops, the Pilot Studies workshops, Functional Assessment and Ambulatory Activity
Monitoring workshops, Disparities Research Curriculum, shared research education and pilot
studies with the CTSA, and inclusion of community representatives in the pilot study selection
process.

## Key facts

- **NIH application ID:** 9971412
- **Project number:** 5P30AG028716-15
- **Recipient organization:** DUKE UNIVERSITY
- **Principal Investigator:** MIRIAM C. MOREY
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $1,078,245
- **Award type:** 5
- **Project period:** 2006-09-15 → 2021-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9971412

## Citation

> US National Institutes of Health, RePORTER application 9971412, Duke Claude D. Pepper Older Americans Independence Center (5P30AG028716-15). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/9971412. Licensed CC0.

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