# Analytical Resources Core

> **NIH NIH U2C** · VANDERBILT UNIVERSITY · 2020 · $287,310

## Abstract

The Analytical Resources Core (ARC) has been an integral part of the VMMPC since it was founded in 2001.
The ARC will consist of four subcores: 1) Hormone Assay and Analytical Services; 2) Lipids, Lipoproteins, and
Atherosclerosis (LLA); 3) Mouse Pathology; and 4) Metabolic Flux Analysis (MFA). Throughout its history the
ARC has operated at capacity with usage by investigators both inside and outside Vanderbilt. The ARC will
undergo two major changes this cycle. The first change is that mouse atherosclerosis and plaque composition
analyses will be moved to the ARC where they will be part of the Lipids, Lipoproteins and Atherosclerosis
(LLA) Subcore. The second modification to the ARC is the creation of the Metabolic Flux Analysis (MFA)
Subcore. The MFA Subcore involves the use of newly developed stable isotopic methods to assess metabolic
flux in the conscious mouse or in vitro model systems. The goals of the core are to provide controlled,
precision services that streamline research activities, produce cost-effective lines of experimentation, foster
collaborative enterprises, and provide alternative outlets to scientists reaching the technical limits of their own
laboratories. The services offered by each subcore are unique in their application to the mouse, and great
effort has been made to establish assay specificity and scale down sample size to accommodate samples from
this species. The Core provides space, equipment, and personnel for sample analyses and methods
development. Investigators pay a fee-for-service that covers the cost of reagents, supplies, a percentage of
personnel salary, and service contracts.

## Key facts

- **NIH application ID:** 9972941
- **Project number:** 5U2CDK059637-20
- **Recipient organization:** VANDERBILT UNIVERSITY
- **Principal Investigator:** MACRAE F LINTON
- **Activity code:** U2C (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $287,310
- **Award type:** 5
- **Project period:** — → 2022-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9972941

## Citation

> US National Institutes of Health, RePORTER application 9972941, Analytical Resources Core (5U2CDK059637-20). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/9972941. Licensed CC0.

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