# Alzheimer's Disease Core Center

> **NIH NIH P30** · NORTHWESTERN UNIVERSITY · 2020 · $2,415,841

## Abstract

PROJECT SUMMARY – OVERALL COMPONENT
The Northwestern ADC is in its 20th year. This renewal application describes the progress of the past cycle
and a plan of action for the next 5 years, during which we will pursue the following principal goals:
A) Support innovative research at Northwestern University on the biology, early diagnosis, risk factors, and
treatment of dementias by bringing together basic and clinical investigators.
B) Participate in national collaborations that leverage the strengths of the NIA Centers by using the UDS,
transmitting data to NACC, and participating in ADNI, ADCS, NCRAD, LOAD and ADGC.
C) Serve a leadership role in FTLD neuropathology, primary progressive aphasia (PPA) and unusually
successful brain aging in keeping with the unique strengths of the Northwestern ADC in this area of aging and
dementia research.
D) Train fellows and junior faculty and attract new investigators to dementia research through accredited
clinical fellowships and training grants.
E) Ensure that patients, families, and underserved populations are beneficiaries of relevant advances through
education, outreach, and novel life enrichment programs.
The cores of the ADC are configured to serve the specific goals listed above. The Administrative Core will be
responsible for the clinical, scientific and fiscal leadership of the entire ADC, as well as the coordination with
national consortia and the selection of projects for pilot funding. The Clinical Core will maintain a cohort of
characterized subjects recruited to address ongoing research priorities. The Data Management and Statistics
Core will ensure that the data are stored in ways that maximize collaboration and that biostatistic analysis
plays a key role in the design and interpretation of research. The Neuropathology Core will characterize
patients who come to autopsy according to up-to-date criteria, and distribute tissue, slides, DNA, and data for
local and national collaborations. The Outreach and Recruitment Core will work with the Clinical Core to
enhance subject recruitment into the ADC, and will develop innovative life enrichment programs to serve
patients and their families. The Research Education Component will oversee diversity recruitment for
researchers and junior faculty and will coordinate training requirements for the Responsible Conduct of
Research. The Executive Committee, composed of all key personnel, will formulate Center priorities based on
local and national mandates and will review requests for patients, controls, tissue, and data according to these
priorities.

## Key facts

- **NIH application ID:** 9973036
- **Project number:** 5P30AG013854-25
- **Recipient organization:** NORTHWESTERN UNIVERSITY
- **Principal Investigator:** ROBERT J VASSAR
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $2,415,841
- **Award type:** 5
- **Project period:** 1997-07-15 → 2022-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9973036

## Citation

> US National Institutes of Health, RePORTER application 9973036, Alzheimer's Disease Core Center (5P30AG013854-25). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/9973036. Licensed CC0.

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