# Strengthening Translational Research in Diverse Enrollment (STRIDE)

> **NIH NIH U01** · UNIV OF MASSACHUSETTS MED SCH WORCESTER · 2020 · $995,729

## Abstract

ABSTRACT
The goal of STRIDE (Strengthening Translational Research in Diverse Enrollment) is to develop, test, and
disseminate an integrated multi-level, culturally sensitive intervention to engage African Americans and Latinos
in translational research. STRIDE is a partnership of the CTSAs at the University of Massachusetts Medical
School, the University of Alabama at Birmingham, and Vanderbilt University, three geographically diverse
areas with large numbers of African American and Latino constituents. Despite disparities in leading causes of
death, morbidity and disability, African Americans and Latinos are under-represented in important translational
research studies that have potential to reduce these disparities. Our team's prior work suggests that limited
research literacy, defined as “the capacity to obtain, process and understand basic information needed to
make informed decisions about research participation,” often precludes research participation. Participant
barriers also include lack of trust stemming from historical abuses. Research team members often lack skills in
cultural competency and may not be sensitive to important issues faced by populations of color. Likewise,
informed consent procedures contained within the research system may create confusion and disengagement
of diverse participants. The multilevel STRIDE intervention will address these barriers at three levels: patient,
research team, and system. The STRIDE intervention builds from synergistic work conducted at the three
participating CTSA hubs that includes patient, research staff and systems (e-Consent) targeted interventions.
Collectively, our approach will enable research personnel to recruit and deliver informed consent in a culturally
competent, literacy appropriate manner, while also improving the “research literacy” of potential research
participants. The participant component of the STRIDE intervention will draw upon the power of narrative
intervention, or “storytelling,” by harnessing powerful stories from actual research participants describing their
experiences, which will be incorporated in community-based outreach forums, the e-consent platform and in
clinical settings. The research team component of the STRIDE intervention centers on an innovative
application of medical simulation to improve the cultural competency of those recruiting and enrolling diverse
participants in translational research. The systems component of the STRIDE intervention will be based on an
innovative REDCap e-Consent platform adapted for cultural sensitivity to African American and Latinos and
incorporates access to ancillary tools to enhance patient understanding. The project has three Specific Aims
that correspond to three study phases. In Aim 1, the comprehensive intervention will be developed and pilot
tested. In Aim 2, a multi-site interrupted time series design trial will be conducted to determine the impact of the
STRIDE intervention on recruitment of African American and L...

## Key facts

- **NIH application ID:** 9975248
- **Project number:** 5U01TR001812-05
- **Recipient organization:** UNIV OF MASSACHUSETTS MED SCH WORCESTER
- **Principal Investigator:** JEROAN J ALLISON
- **Activity code:** U01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $995,729
- **Award type:** 5
- **Project period:** 2016-09-08 → 2022-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9975248

## Citation

> US National Institutes of Health, RePORTER application 9975248, Strengthening Translational Research in Diverse Enrollment (STRIDE) (5U01TR001812-05). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/9975248. Licensed CC0.

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