# Microscopy Shared Resource

> **NIH NIH P30** · COLD SPRING HARBOR LABORATORY · 2020 · $194,191

## Abstract

Microscopy Shared Resource - Project Summary/Abstract
The Microscopy Shared Resource was developed in concert with the initiation of the Cold Spring Harbor
Laboratory (CSHL) Cancer Center in 1986, and has been continuously serving Cancer Center members since
that time. The Microscopy Shared Resource is widely used; over the last funding period, it was used by 78%
of the Cancer Center membership (29 members). The Shared Resource provides Cancer Center members
with access to state-of-the-art microscope instrumentation and sophisticated technical expertise. Among the
types of services rendered are wide-field fluorescence microscopy, deconvolution microscopy, confocal
microscopy including point-scanning and spinning disk, live cell imaging, super-resolution structured
illumination microscopy, standard transmission electron microscopy, immunoelectron microscopy (enzymatic
and gold labeling), and evaluation of subcellular fractionation procedures by negative staining or thin
sectioning. In addition, training is available for several image analysis programs to allow users to analyze
imaging data. All of these services are highly technical and labor intensive. Without the Microscopy Shared
Resource, it would be extremely difficult for individual investigators to have access to this sophisticated
instrumentation and these types of services, which are critical to their research programs. In addition, the
Microscopy Shared Resource serves as a central focal point where users can interact, learn about new
imaging technologies, discuss availability of fluorescent proteins/probes or antibodies, and gain insight into
imaging approaches that will advance their science. Over the past funding period, the Microscopy Shared
Resource moved into a newly renovated building with temperature controlled imaging rooms. In addition,
CSHL has acquired support to purchase two new microscope systems: a Zeiss LSM780 point-scanning
confocal microscope and a Perkin Elmer UltraVIEW VoX high speed spinning disk laser confocal microscope.
In summary, the Microscopy Shared Resource provides the user group with a complete complement of state-
of-the-art instrumentation and advanced technical support to help accelerate cancer research and discovery.

## Key facts

- **NIH application ID:** 9975721
- **Project number:** 5P30CA045508-33
- **Recipient organization:** COLD SPRING HARBOR LABORATORY
- **Principal Investigator:** DAVID L SPECTOR
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $194,191
- **Award type:** 5
- **Project period:** — → —

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9975721

## Citation

> US National Institutes of Health, RePORTER application 9975721, Microscopy Shared Resource (5P30CA045508-33). Retrieved via AI Analytics 2026-05-29 from https://api.ai-analytics.org/grant/nih/9975721. Licensed CC0.

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