# Drug Discovery, Delivery, & Experimental Therapeutics Research Program

> **NIH NIH P30** · UNIVERSITY OF KANSAS MEDICAL CENTER · 2020 · $69,699

## Abstract

Drug Discovery, Delivery and Experimental Therapeutics – Project Summary 
The Drug Discovery, Delivery and Experimental Therapeutics (D3ET) research program integrates a broad 
range of research areas that contribute to the discovery and delivery of new cancer therapeutic strategies, 
identification of companion biomarkers, translation of the most promising therapeutic strategies to the clinic 
and the evaluation of these strategies in experimental therapeutics trials. D3ET is organized around three, 
central highly-integrated scientific themes: 1) Discover and Deliver New Cancer Therapeutic Strategies; 2) 
Develop New Cancer Therapeutic Strategies; and 3) Evaluate New Cancer Therapeutic Strategies in 
Experimental Therapeutics Trials. D3ET has 60 members (33 PhD's and 27 MD's), including 39 full and 21 
associate members. Membership reflects a range of senior and early-stage investigators with 20 Professors, 
13 Associate Professors and 17 Assistant Professors. D3ET members are drawn from 25 departments across 
Children's Mercy, The University of Kansas in Lawrence and The University of Kansas Medical Center in 
Kansas City, providing a rich environment for discipline diversity and team science. 
During the reporting period (CY15), 51% of the 39 full members serve as principal investigators on externally 
funded, peer-reviewed grants. From 2012-2015, the D3ET program achieved a strong and growing cancer- 
focused research portfolio. In 2015, D3ET members conducted research on 36 cancer-relevant, peer-reviewed 
projects representing $9.1M in extramural funding, including $3.1M in funding obtained directly from the 
National Cancer Institute (NCI). The 15 NCI funded grants represented 35% of total peer-reviewed funding. 
D3ET has grown clinical research primarily by members successfully obtaining grants from industry to support 
clinical trial activities. The D3ET program has made impressive progress in publishing its research, and 
increasing intra-programmatic and inter-programmatic collaborations. Between 2012 and 2015, D3ET 
members published 617 cancer-relevant publications, including 67 papers with a journal impact factor of ≥8. 
Twenty-nine percent of D3ET published research over this time period represented intra-programmatic 
collaborations and 23% involving inter-programmatic collaborations. Consistent with its research themes and 
objectives, 51% of D3ET publications included external industry, academia, government or disease 
philanthropy collaborators. Alan Gamis, MD (Children's Mercy) and Scott Weir, PharmD, PhD (KUMC), who 
bring complimentary scientific expertise in drug discovery, development and experimental therapeutics and 
strong track records of mentorship, jointly lead D3ET. Steve Williamson, MD, Medical Director for the Clinical 
Trials Office and D3ET member, completes the leadership team representing adult cancer experimental 
therapeutics.

## Key facts

- **NIH application ID:** 9975745
- **Project number:** 5P30CA168524-09
- **Recipient organization:** UNIVERSITY OF KANSAS MEDICAL CENTER
- **Principal Investigator:** JOHN A TAYLOR
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $69,699
- **Award type:** 5
- **Project period:** 2012-07-11 → 2022-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9975745

## Citation

> US National Institutes of Health, RePORTER application 9975745, Drug Discovery, Delivery, & Experimental Therapeutics Research Program (5P30CA168524-09). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/9975745. Licensed CC0.

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