# Center for Prevention Implementation Methodology for Drug Abuse and HIV (Ce-PIM)

> **NIH NIH P30** · NORTHWESTERN UNIVERSITY · 2020 · $1,040,945

## Abstract

PROJECT SUMMARY/ABSTRACT
 This application is for a competing renewal of the Center for Prevention Implementation Methodology
for HIV and Drug Abuse, a NIDA P30 Center of Excellence. The number of new HIV cases in the US
remains stable at 56,000 per year and continues to disproportionately affect some groups, including young
men who have sex with men (YMSM), especially from racial/ethnic minorities. The purpose of this
methodology center is to develop new methodologies that can be used by federal and local agencies and
communities to reduce HIV incidence. Biomedical interventions and strategies, including pre-exposure
prophylaxis (PrEP), rapid testing for HIV and early and consistent treatment for persons who are HIV
positive (Treatment as Prevention, TasP) have been shown to have high efficacy and effectiveness in
reducing HIV transmission, but there remains a giant gap between what research knows and what services
needed to reduce population level incidence of HIV. The major premise of this application is that the
effective biomedical to reduce HIV incidence and disparities are in hand, but success will only be
achieved when they are implemented in ways that meet individual, community, and health care delivery
system needs. This methods proposal addresses this major gap between research and practice through
implementation science and methodology, focusing on innovative ways to address the complex,
mulitilevel interactions needed to implement HIV prevention programs effectively. Two Cores, an
Administrative Core and an Innovative Implementation Methods Core for HIV and Drug Abuse will carry out
this work.
 Aim 1 is to develop innovative methods to maximize the impact of implementation research in
HIV prevention. We do this through an extended set of systems science and engineering methods that
focus on improving the measurement of implementation, the modeling of implementation strategies, and the
testing of implementation strategies through rigorous trials. Five qualifying grants support this work.
 Aim 2 is to apply these innovative methods to close the gap between existing research, policy, and
practice for HIV prevention. In addition to working closely with our five qualifying grants, we work locally with
municipal Departments of Public Health and the federal Substance Abuse and Mental Health
Services Administration (SAMHSA) HIV programs to identify and prioritize gaps in knowledge,
find optimal implementation strategies for reduction of HIV transmission, and design the next large
implementation trials.
 Aim 3 is to disseminate methods and train/mentor leaders at the intersection of HIV
prevention, implementation science, and drug abuse fields to improve implementation of HIV prevention
programs. This involves mentoring the early career researchers, publishing, and providing training to networks
of HIV and drug abuse researchers.

## Key facts

- **NIH application ID:** 9975784
- **Project number:** 5P30DA027828-10
- **Recipient organization:** NORTHWESTERN UNIVERSITY
- **Principal Investigator:** C. HENDRICKS BROWN
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $1,040,945
- **Award type:** 5
- **Project period:** 2011-08-15 → 2022-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9975784

## Citation

> US National Institutes of Health, RePORTER application 9975784, Center for Prevention Implementation Methodology for Drug Abuse and HIV (Ce-PIM) (5P30DA027828-10). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/9975784. Licensed CC0.

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