# Onco-Genomics Shared Resources

> **NIH NIH P30** · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · 2020 · $194,722

## Abstract

PROJECT SUMMARY: ONCO-GENOMICS SHARED RESOURCE
The Onco-Genomics Shared Resource (OGSR) provides members of the Sylvester Comprehensive Cancer
Center (Sylvester) access to technology platforms and assays for studying the genomics and epigenetics of
cancer that are far too specialized for any one laboratory to support on its own. The OGSR employs four full-
time technicians and one part-time technician who are cross-trained on workflows and quality control
assessments. The facility is charged with providing rapid turnaround times, a service menu tailored to
Sylvester investigator needs, and cost-effective use of resources. Next generation sequencing (NGS) capacity
is maximized with automated library preparation and the ability to simultaneously run two different sequencing
chemistries. State-of-the-art instrumentation includes two Illumina NextSeq 500 benchtop sequencers, a Perkin
Elmer Zephyr G3 NGS liquid handler, a 10x Genomics Chromium single cell controller, and a nanoString MAX
system. NGS services support RNA-seq of all types and DNA-seq for epigenetics workflows, such as ChIP-seq
and ATAC-seq. Additionally, staff work closely with investigators to develop workflows for challenging library
types and single cell experiments. The OGSR also offers basic services for investigators who lack laboratory
resources, such as sample extraction and quality control, to assist in furthering translational research. In
coordination with the Biostatistics and Bioinformatics Shared Resource (BBSR) and the Flow Cytometry
Shared Resource (FCSR), the OGSR provides expert support for experimental design and data interpretation
to optimize grant applications and drive post-award science. In 2017, the OGSR provided services to 27
Sylvester investigators (89% of whom were supported by peer-reviewed funding). Sylvester members comprise
69% of total OGSR users.

## Key facts

- **NIH application ID:** 9975823
- **Project number:** 5P30CA240139-02
- **Recipient organization:** UNIVERSITY OF MIAMI SCHOOL OF MEDICINE
- **Principal Investigator:** SION LLEWELYN WILLIAMS
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $194,722
- **Award type:** 5
- **Project period:** — → —

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9975823

## Citation

> US National Institutes of Health, RePORTER application 9975823, Onco-Genomics Shared Resources (5P30CA240139-02). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/9975823. Licensed CC0.

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