# Core C: Data Management and Statistical Core

> **NIH NIH P30** · UNIVERSITY OF KENTUCKY · 2020 · $289,327

## Abstract

Program Summary/Abstract: Data Management and Statistical Core
The Data Management and Statistical (DMS) Core can be conceptualized as the lynchpin for integration of the
ADC Cores and is vital to the success of the UK-ADC. Its critical roles include managing a large centralized
database, consulting with ADC-affiliated researchers, and working to develop and apply innovative statistical
methodology for data analysis. Data management efforts focus on collecting and storing high quality data.
This focus begins with the leadership and vision and attention to detail provided by the DMS Core. This core
has an enviable track record of timely and accurate reporting of a high volume of data to NACC. Further,
weekly Core meetings are popular with UK-ADC investigators who find that the expert advice provided by our
seasoned investigators improves their success in pilot studies, grant applications, and publications. The Core
also participates as a full partner to the research mission of the UK-ADC emphasizing transitions and
translations. One such partnership with the Clinical and Neuropathology Cores relates to clinico-pathological
models of mixed dementias. A key element of this DMS Core is the well-established track record of developing
novel methodology to analyze data collected at the UK-ADC and from other cohorts with a focus on elderly
subjects’ transitions to MCI and eventually dementia. The Core also provides training for students enrolled in
the graduate programs in Gerontology, Public Health, Epidemiology and Biostatistics, Psychology, and
Statistics. It is committed to developing younger faculty to become productive ADC investigators. In keeping
with the mission of the UK-ADC, faculty in this Core also contribute to the dementia research community at
large through service on external advisory committees, study sections, manuscript reviews, and data safety
monitoring boards. The DMS Core will continue these critical responsibilities through the following specific
aims.
1: Create and maintain a web-based, integrated data warehouse for ADC Cores and projects.
2: Provide expertise on experimental design and statistical analysis.
3: Support the clinical, neuropathological, and educational/outreach missions of the ADC.
4: Contribute to the activities of the dementia community at large through service and research.

## Key facts

- **NIH application ID:** 9976434
- **Project number:** 5P30AG028383-15
- **Recipient organization:** UNIVERSITY OF KENTUCKY
- **Principal Investigator:** Richard J. Kryscio
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $289,327
- **Award type:** 5
- **Project period:** — → 2023-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9976434

## Citation

> US National Institutes of Health, RePORTER application 9976434, Core C: Data Management and Statistical Core (5P30AG028383-15). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/9976434. Licensed CC0.

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