# Tumor Cell Biology Training Program

> **NIH NIH T32** · UNIVERSITY OF CALIFORNIA LOS ANGELES · 2020 · $511,197

## Abstract

Abstract/Summary
The overarching goal of the Tumor Cell Biology Training Program (TCB-TP) is to equip the next generation of
cancer biologists and clinician scientists with the tools essential for innovative research. Recent improvements
in the diagnosis and treatment of cancer have been driven by the translation of paradigm-shifting basic research
into clinical settings. Continued progress toward complete remission or cure of all cancer types will require an
intensified effort on multiple fronts. For this to occur, it is essential that the next generation of cancer researchers
have the knowledge, analytical tools, and critical thinking skills to integrate diverse fields of biology. In addition,
it is imperative that basic science researchers be able to access and integrate the insights being generated by
clinical researchers. We undertake this mission using two complementary approaches. The first is to provide
comprehensive training in the fundamental and emerging mechanisms of tumor biology and the range of tools
available to study these processes. The second is to provide a forum in which basic studies in tumor biology are
viewed within the context of their relevance to diagnostics and therapeutics. These objectives are achieved
through the participation of trainees and faculty with a diverse range of scientific interests and expertise in both
basic and translational research. The training program brings together three pre-doctoral and five post-doctoral
trainees, who are supported for at least two years while they conduct mentored research projects. Trainee
mentors are drawn from twenty-four Ph.D. and M.D. program faculty members who are affiliated with 12 different
UCLA departments, and whose areas of research include cancer-initiating cells, transcriptional regulation, tumor
micro-environment, metabolism, computational biology, and cell division. A monthly seminar series brings
together trainees and faculty to critically discuss research data presented by each trainee. The program
leadership invites at least one translational and/or clinical investigator who has expertise in the topic under
discussion and can contribute a clinical perspective to the seminar. One-on-one meetings between program
leadership and trainees are designed to provide feedback on seminar content and effectiveness of the
presentation, encourage trainees to discuss their progress and plans, and offer trainees an opportunity to
express any concerns about their training environment. A written Individual Development Plan is completed
annually by trainees and reviewed with the PIs and co-investigator. Courses on ethics and reproducibility in
research are mandatory for all trainees. The Tumor Cell Biology Training Program will be jointly directed under
the multi-PI mechanism by Dr. Gay M. Crooks and Dr. Owen N. Witte, senior academic leaders at UCLA with
well established programs in basic and translational research. The program enjoys strong campus support from,
among others...

## Key facts

- **NIH application ID:** 9976462
- **Project number:** 5T32CA009056-44
- **Recipient organization:** UNIVERSITY OF CALIFORNIA LOS ANGELES
- **Principal Investigator:** Gay M Crooks
- **Activity code:** T32 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $511,197
- **Award type:** 5
- **Project period:** 1980-07-01 → 2022-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9976462

## Citation

> US National Institutes of Health, RePORTER application 9976462, Tumor Cell Biology Training Program (5T32CA009056-44). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/9976462. Licensed CC0.

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