# An Administrative Core for the CaST Center

> **NIH NIH U54** · COLUMBIA UNIVERSITY HEALTH SCIENCES · 2020 · $278,696

## Abstract

PROJECT SUMMARY
The Administrative Core will provide coordination and oversight across all Center activities. It will help
maximize interactions and synergies, enable optimal use of available research infrastructure such as the
Center's state-of-the-art High Performance Computing Environment, facilitate the participation of Center
members to the activities of the Cancer Systems Biology Consortium (CSBC), ensure that input from
Consortium activities is properly integrated into the Center's research program, and administer a pilot research
fund which will support one-year intra-Center research projects contributing to the overall Center research
theme. An effective management structure will be put in place to ensure that these objectives are achieved,
including an Executive Steering Committee (comprising the Center's Directors, Project Manager, and NCI
program officers) that will establish the direction of the Center's program and provide overall guidance; and a
Project Manager who will meet frequently with project and core leads to ensure that planned work is
proceeding according to schedule, that operational problems are quickly resolved, and that software, data, and
models generated by project activities are released to the public in a timely manner, liaising with the CSBC
Data Coordination Center as needed. To further promote integration of the program and effective
communication among its various members, the Core will organize monthly meetings comprised of two parts:
(i) research presentations, which will include all program participants, and (ii) executive meetings, which will be
limited to the Executive Steering Committee. The latter will provide a forum for candid assessment of project
progress and prioritization of resources and objectives. It will also offer an opportunity to explore possible
interactions and collaborations with other CSBC Centers and related NCI/NIH initiatives.
An important function of the Administrative Core will be to provide logistical support through management of
data and resources, fiscal review and budget analysis, preparation of progress reports, and compliance with
regulatory requirements. A qualified Center Administrator will be appointed to assist the Center's Directors and
Project Manager with the execution of these tasks. The Core will be responsible for assembling a world class
scientific External Advisory Committee (EAC) to advise the Center's Directors and to provide an impartial
assessment of the Center's research program. The Core will organize an annual review meeting where the
EAC members will be asked to offer feedback on research progress and future directions, as well as advice on
program management and the administration of the pilot project progam. The Core will also be responsible for
defining and tracking a broad collection of quantitative evaluation metrics to assess the quality and utility of the
Center's products. Finally, the Administrative Core will coordinate the participation of Center...

## Key facts

- **NIH application ID:** 9976478
- **Project number:** 5U54CA209997-05
- **Recipient organization:** COLUMBIA UNIVERSITY HEALTH SCIENCES
- **Principal Investigator:** ANDREA CALIFANO
- **Activity code:** U54 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $278,696
- **Award type:** 5
- **Project period:** — → 2022-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9976478

## Citation

> US National Institutes of Health, RePORTER application 9976478, An Administrative Core for the CaST Center (5U54CA209997-05). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/9976478. Licensed CC0.

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