# Arizona Alzheimer's Disease Core Center

> **NIH NIH P30** · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · 2020 · $2,978,035

## Abstract

OVERALL - PROJECT SUMMARY/ABSTRACT
 The Arizona Alzheimer's Disease Core Center (ADCC) capitalizes on its leadership, resources, and
collaborative model to advance the study of AD, related disorders, and the aging mind and brain. It provides a
springboard as well as support for productive programs and partnerships, and leverages its resources and
resulting programs to accelerate the evaluation of prevention therapies, and make the fight against AD a top
statewide priority. The Administrative Core provides the ADCC's leadership, relationships, direction, and
support; and ensures that the Cores and Research Education Component (REC) are optimally developed,
utilized, and working together. It administers a Pilot Project Program for new investigators; launches new
programs and partnerships; and works closely with NIA, National Alzheimer's Coordinating Center (NACC),
other AD Centers, and numerous other organizations to ensure that state and organizational funds, Ancillary
Cores, and other resulting programs are used to fulfill the ADCC's overarching goals. The multi-site Clinical
Core and its Ancillary Cores provide and support the productive use of NACC-uploaded data, blood samples
and DNA from annually assessed patients with AD dementia, other dementias, and mild cognitive impairment
(MCI), as well as cognitively unimpaired older adults in our Brain and Body Donation Program (BBDP),
cognitively unimpaired and longitudinally assessed apolipoprotein E4 (APOE4) homozygotes, heterozygotes
and non-carriers for the study of preclinical AD, and a growing number of Latinos and Native Americans. The
Data Management and Statistics (DMS) Core provides a comprehensive data management program for the
acquisition, quality-assurance, organization, appropriate use, and NACC-uploading of ADCC data and the
assessment of ADCC performance; biostatistical expertise, mentorship, training, and support; and new
computational, mathematical, and statistical data analysis tools to address their goals with improved power.
The Neuropathology Core provides extremely rapid autopsies, exceptionally high-quality brain and body tissue,
comprehensive neuropathological assessments, diagnoses, and research services, NACC-uploaded UDS
data, and numerous tissue distributions from many cognitively impaired and unimpaired brain donors in the
ADCC and Ancillary BBDP Cores. The Outreach and Recruitment (OR) Core supports recruitment and
retention of Clinical Core and other research participants; provides extensive education and outreach services
and interactions with community stakeholders; helps address the needs of understudied and underserved
Latinos and Native Americans; develops and tests innovative dementia care programs; and supports
development and use of the Alzheimer's Prevention Registry. The new Research Education Component (REC)
provides a large and growing number of research mentors and multi-disciplinary research, training, and
educational activities to support the developmen...

## Key facts

- **NIH application ID:** 9977063
- **Project number:** 5P30AG019610-21
- **Recipient organization:** ARIZONA STATE UNIVERSITY-TEMPE CAMPUS
- **Principal Investigator:** ERIC MICHAEL REIMAN
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $2,978,035
- **Award type:** 5
- **Project period:** 2001-09-30 → 2023-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9977063

## Citation

> US National Institutes of Health, RePORTER application 9977063, Arizona Alzheimer's Disease Core Center (5P30AG019610-21). Retrieved via AI Analytics 2026-06-10 from https://api.ai-analytics.org/grant/nih/9977063. Licensed CC0.

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