# Core C: Data Management and Statistical Core

> **NIH NIH P30** · RUSH UNIVERSITY MEDICAL CENTER · 2020 · $355,045

## Abstract

ABSTRACT – DATA MANAGEMENT AND STATISTICAL CORE
The Data Management and Statistical Core of the Rush ADCC designs and maintains systems to support the
acquisition, maintenance, distribution and analysis of high-quality data collected by the Clinical,
Neuropathology, Religious Orders Study and Latino Cores of the ADCC. These data are a resource for
ongoing and future research on normal aging, MCI, Alzheimer’s Disease, other neurodegenerative diseases,
and AD and mixed pathologies.
The Data Management and Statistical Core will support the other cores in the Center by (1) maintaining a
center-wide system of random subject ID numbers, (2) maintaining PC- and web-based electronic data
collection systems for each core to collect data, (3) processing and maintaining item-level data in a secure
relational database management system, (4) managing storage of high throughput files containing biochemical
and molecular data, (5) storing computed summary variables in a secure relational database management
system, (6) providing flexible, comprehensive, automatic and timely status reports for study coordination, and
(7) designing, maintaining and tracking usage of the Center’s internal and external websites. The Data
Management and Statistical Core will also maintain tracking systems for (1) scheduling and prioritizing study
participants and biospecimens for the Clinical, Neuropathology, Religious Order Study, and Latino Cores, (2)
tracking biospecimen inventory and requests for distributions for Neuropathology and Administrative Cores, (3)
tracking data requests and distributions for the Administrative Core, (4) tracking activities and outcomes for
the Outreach and Recruitment Core and for the Research Education Component, (5) tracking publications
using Rush ADCC resources, and (6) prioritization of data management and statistics activities.
The Core will provide expert statistical assistance with design and analysis to Rush ADCC investigators and
pilot project applicants and awardees, and more limited guidance to independently funded studies that utilize
Rush ADCC data and/or specimens.
The Core will operate a system for building data sets in the Neuropathology (NP) and Uniform Data Set (UDS)
formats for transmission to NACC that will ensure that data are accurately shared at regular intervals and in a
timely manner.
The Core will support systems for providing data to support externally funded projects and secondary
analyses, with an emphasis on projects funded by the National Institutes of Health and other reputable
research organizations. The Data Management and Statistical Core will maintain an online system for
investigators inside or outside the Rush ADCC to submit requests for Rush ADCC data and biospecimens.
The Core will maintain tools that extract approved datasets for distribution, and generate accompanying clear
and accurate data element dictionaries.

## Key facts

- **NIH application ID:** 9977089
- **Project number:** 5P30AG010161-30
- **Recipient organization:** RUSH UNIVERSITY MEDICAL CENTER
- **Principal Investigator:** Sue E. Leurgans
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $355,045
- **Award type:** 5
- **Project period:** — → 2023-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9977089

## Citation

> US National Institutes of Health, RePORTER application 9977089, Core C: Data Management and Statistical Core (5P30AG010161-30). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/9977089. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*