# Genetics, Biomarker and Bioinformatics Core

> **NIH NIH P30** · INDIANA UNIVERSITY INDIANAPOLIS · 2020 · $579,748

## Abstract

Project Summary – Genetics, Biomarker, and Bioinformatics Core (GBBC)
 The Indiana Alzheimer Disease Center (IADC) has a strong history of innovative research in
the genetics of hereditary dementia as well as imaging genomics. Under the recent leadership
transition to Dr. Andrew Saykin, the iADC is building on this legacy to explore the role of
genetics and other types of biomarkers as predictors of clinical trajectories among the broader
group of individuals with subjective cognitive decline (SCD) and mild cognitive impairment
(MCI).
 The Genetics, Biomarker and Bioinformatics Core (GBBC) leverages the unique patient
populations and genomics resources at Indiana University School of Medicine (IUSOM) to
support each of the cores as well as the overall goals of the IADC. The GBBC fosters new
research directions through the common banking of samples from diverse research groups.
These samples are then available to address research questions which are central to the
interests of the IADC. In addition, these samples are available for collaborative studies, thereby
enhancing the power of all ADC studies focused on disease susceptibility, onset and
progression. The specific aims of the GBBC are to:
1. Obtain longitudinal biospecimen samples from all subjects seen in the Clinical Core.
2. Perform detailed genetic studies with individuals and families having early onset dementia.
3. Prepare and distribute biospecimens to support ongoing local and national research studies.
4. Provide education in the areas of genetics and biospecimen collection to researchers
 interested in neurodegeneration.

## Key facts

- **NIH application ID:** 9977806
- **Project number:** 5P30AG010133-30
- **Recipient organization:** INDIANA UNIVERSITY INDIANAPOLIS
- **Principal Investigator:** TATIANA M. FOROUD
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $579,748
- **Award type:** 5
- **Project period:** — → 2022-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9977806

## Citation

> US National Institutes of Health, RePORTER application 9977806, Genetics, Biomarker and Bioinformatics Core (5P30AG010133-30). Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/grant/nih/9977806. Licensed CC0.

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