# The Cirrhosis Medical Home: A Feasibility Study

> **NIH NIH R03** · INDIANA UNIVERSITY INDIANAPOLIS · 2020 · $121,498

## Abstract

PROJECT SUMMARY
Liver cirrhosis places a significant burden on individuals and society, causing diminished quality of life,
increased disability, morbidity, and mortality; and high costs and utilization of health care resources. These
outcomes could be improved with existing resources, but the current fragmented nature of the health care
system does not allow for the necessary coordination to best care for this population. To address the general
lack of care coordination in the health care system, collaborative care models have been developed for a wide
range of clinical settings, and have successfully improved care for patients with numerous chronic diseases.
Researchers at the Indiana University School of Medicine have over 20 years of experience in developing,
testing, and implementing collaborative care for patients with dementia, depression, and other conditions.
Building on these successes, investigators have customized the collaborative care model to best meet the
unique needs of patients with decompensated cirrhosis: The Cirrhosis Medical Home (CMH). This proposal
aims to establish the feasibility of performing a randomized controlled trial comparing the CMH to usual care
for patients discharged from the hospital with decompensated cirrhosis. The specific aims are: (1) to test the
screening and enrollment processes for a randomized trial of the CMH compared to usual care for patients
discharged from the hospital with decompensated cirrhosis; (2) to assess the data collection process, outcome
assessment, and the acceptability of the CMH randomized trial; and (3) to estimate the effect size of the CMH
intervention on quality of life after six months. Upon completion of the proposed study, the investigators will
have demonstrated the feasibility of enrolling and retaining subjects in a randomized trial of the CMH, and they
will have established an estimated effect size that will ensure adequate power for a future randomized trial that
will evaluate the efficacy of the CMH.

## Key facts

- **NIH application ID:** 9978477
- **Project number:** 1R03DK122230-01A1
- **Recipient organization:** INDIANA UNIVERSITY INDIANAPOLIS
- **Principal Investigator:** Eric Orman
- **Activity code:** R03 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $121,498
- **Award type:** 1
- **Project period:** 2020-07-01 → 2022-04-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9978477

## Citation

> US National Institutes of Health, RePORTER application 9978477, The Cirrhosis Medical Home: A Feasibility Study (1R03DK122230-01A1). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/9978477. Licensed CC0.

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