# UW Core Center for Clinical Research (CCCR) of Musculoskeletal Conditions

> **NIH NIH P30** · UNIVERSITY OF WASHINGTON · 2020 · $738,659

## Abstract

The overall aim of our CCCR is to develop and provide scientifically rigorous, state-of-the-art methods
and resources for conducting musculoskeletal clinical research, thereby expanding the community of
investigators performing high-quality musculoskeletal clinical research and thus increasing the
amount of available useful data for researchers, clinicians, patients and policy makers. Over the past
decade, health care systems having become increasingly integrated and use electronic health record systems
that are collecting and archiving comprehensive and complex sets of data on large populations. While the
potential for using such “big data” to address a wide range of health-related questions is enormous, there are
substantial obstacles that prevent researchers from accessing and analyzing routine clinical data. Through
multiple projects focused on musculoskeletal conditions and funded by a variety of entities (NIH, AHRQ and
PCORI), our group at the University of Washington (UW) has accumulated extensive experience and expertise
performing large, clinical, effectiveness trials and transforming routine clinical data into research-ready data.
We have both developed methods and also have accumulated a sizeable amount of cleaned and analyzable
data. Because of our expertise and resources, we believe that we are well-positioned to propose a UW Core
Center for Clinical Research (CCCR) in Musculoskeletal Diseases. Our UW CCCR Specific Aims are: 1)
Establish a Methodologic Core that will improve methods for clinical musculoskeletal studies that use
rigorous and novel study designs, pragmatic/effectiveness clinical trial, and electronic medical records
(EMRs); 2) Establish a Resource Core that will provide analysis-ready data sets and services for
conducting clinical musculoskeletal research; and 3) Establish an Administrative Core that will provide
overall leadership for the CCCR, manage the financial aspects of the CCCR so that it is a sustainable
entity, provide communication and outreach to musculoskeletal researchers and evaluate the success
of our efforts. By achieving these aims, we will improve access to expertise and research-quality data, we will
improve analytics by developing methods and pipelines for the analysis of clinical data, and we will apply and
disseminate knowledge regarding the conduct of rigorous clinical trials. By integrating the viewpoints of
stakeholders, our CCCR will be able to provide useful research data to health system decision-makers who will
apply the results of the research to real-world decisions. By achieving these aims, we will facilitate health care
delivery systems becoming true learning health care systems. Finally and perhaps most importantly, we will
work with training programs (K12, KL2, R25 and T32) to train the next generation of investigators in the
methods and approaches outlined above.

## Key facts

- **NIH application ID:** 9979758
- **Project number:** 5P30AR072572-04
- **Recipient organization:** UNIVERSITY OF WASHINGTON
- **Principal Investigator:** JEFFREY G JARVIK
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $738,659
- **Award type:** 5
- **Project period:** 2017-09-21 → 2022-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9979758

## Citation

> US National Institutes of Health, RePORTER application 9979758, UW Core Center for Clinical Research (CCCR) of Musculoskeletal Conditions (5P30AR072572-04). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/9979758. Licensed CC0.

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