# Oklahoma Shared Clinical and Translational Resources

> **NIH NIH U54** · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · 2020 · $3,936,058

## Abstract

An Oklahoma born in 2010 has the fifth lowest life-expectancy in the US and American Indians have the
shortest, 7.3 years less than the US average. Cancer, diabetes, cardiovascular disease, arthritis, and
autoimmunity are leading causes of disability and early mortality, serving as sources of major health disparities
in Oklahoma and other IDeA-states. Along with these diseases, tobacco use, opioid abuse, and child health
are also prominent health concerns. The primary mission of the Oklahoma Shared Clinical and Translational
Resources (OSCTR) is to improve health by catalyzing clinical and translational research (CTR) in these top
health priorities. To fulfill its mission, the OSCTR integrates health professionals, investigators, and scientific
resources at 29 public, private, and tribal partners/affiliate partners statewide. Oklahoma is an ideal setting for
these efforts due to these high rates of chronic diseases, and large rural and tribal populations where improved
health outcomes may serve as models across IDeA states. CTR on tribal health priorities and health equity is
fostered by strong relationships between OSCTR research institutions and tribal nations/health systems.
OSCTR houses the only CAP-certified biorepository affiliated with an IDeA-CTR, and cutting-edge resources
for data research and medical data warehouses. Oklahoma also has a growing cadre of junior investigators
who are launching independent CTR careers (most with OSCTR assistance), with institutional leaders who are
committed to CTR and improving Oklahomans health. Concurrent with these strengths, the OSCTR is
leveraging new partnerships to move toward prevention. Although many early successes are evident, CTR
sustainability in Oklahoma and its impact on public health are limited by ongoing needs for infrastructure
support and by a need for further development of the nascent clinical research infrastructure. Therefore, to
expand research into diseases with high prevalence in rural and tribal populations, the OSCTR is helping tribal
health systems build CTR infrastructure and fostering interactions through the Tribal Engagement Unit. To
launch independent CTR careers of junior investigators from multiple disciplines, the OSCTR provides training,
mentoring, pilot grants, and infrastructure. This includes patient registries, repositories, and data warehouses;
recruiting and regulatory support; biostatistical and epidemiologic expertise; and comprehensive online
resources linking investigators to relevant Core facilities at each OSCTR partner institution and Oklahoma
IDeA program. To engage health professionals, communities, and patients in high-priority CTR, the OSCTR
will develop an expanded online portal to educate patients and providers on CTR, and leverages a large
network of community-oriented health improvement organizations. Finally, to develop and share effective
infrastructure, the OSCTR collaborates with biomedical IDeA programs in Oklahoma and other states.
Togethe...

## Key facts

- **NIH application ID:** 9979908
- **Project number:** 5U54GM104938-08
- **Recipient organization:** UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR
- **Principal Investigator:** JUDITH A JAMES
- **Activity code:** U54 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $3,936,058
- **Award type:** 5
- **Project period:** 2013-09-01 → 2023-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9979908

## Citation

> US National Institutes of Health, RePORTER application 9979908, Oklahoma Shared Clinical and Translational Resources (5U54GM104938-08). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/9979908. Licensed CC0.

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