# Scientific Core (ETR)

> **NIH NIH U19** · FLORIDA STATE UNIVERSITY · 2020 · $387,809

## Abstract

The implementation science literature underscores the challenges associated with moving research to routine
practice, and acknowledges the importance of building the literature base to facilitate scale-up of evidencebased
practices. In our proposed U19, our interdisciplinary research team is committed to working with HIV+
youth and youth at risk of infection to improve their health and well-being and to develop the IS field by
employing three types of effectiveness-implementation hybrid designs, all addressing self-management: 1) a
Type 1 design (Belzer and Brown) in which the primary aim is to determine the effectiveness of clinical
intervention with a secondary aim to better understand the context for implementation; 2) a Type 2 design
(Parsons) in which the primary aims are to determine both the effectiveness of the clinical intervention and the
feasibility and utility of an implementation strategy; and 3) a Type 3 design (Naar), in which the primary aim is
to determine the utility of an implementation strategy with a secondary aim on assessing effectiveness on
cascade-related outcomes. Consistent with our overall goal of advancing implementation science, our team
has established an Implementation Science Core (ISC) to maximize efficiencies across projects and has
adopted an implementation conceptual model, Exploration-Preparation-Implementation-Sustainment (EPIS), to
ground implementation planning, research, and measurement across the studies. In particular, the Research
Projects will examine EPIS inner and outer context factors across phases—from exploring ways to improve fit
to characteristics that may influence active implementation, such as the sociopolitical context, leadership,
facilitator attitudes toward evidence-based practices, fiscal viability, and acceptability and feasibility of
interventions. Specifically, the ISC will: (1) facilitate and support a unified approach to implementation science
research particularly as it applies to self-management by HIV+ or at risk youth; (2) provide resources to
support early career and other investigators in the newly developed ATN4 with implementation science issues
related to their studies; and (3) increase dissemination of interventions, support materials, and implementation
study findings relevant to adolescent HIV/AIDS prevention and treatment. The inclusion of the ISC provides an
opportunity for synergy across Research Projects to systematically expand the implementation science
research related to youth HIV self-management interventions, a contribution to field and to those looking
towards avenues of scaling up such interventions.

## Key facts

- **NIH application ID:** 9980430
- **Project number:** 5U19HD089875-06
- **Recipient organization:** FLORIDA STATE UNIVERSITY
- **Principal Investigator:** KARIN Kristina COYLE
- **Activity code:** U19 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $387,809
- **Award type:** 5
- **Project period:** — → 2022-11-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9980430

## Citation

> US National Institutes of Health, RePORTER application 9980430, Scientific Core (ETR) (5U19HD089875-06). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/9980430. Licensed CC0.

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