# Core F: Research Education Component (RL5)

> **NIH NIH P30** · WAKE FOREST UNIVERSITY HEALTH SCIENCES · 2020 · $48,119

## Abstract

Research Education Component Core (Core F) – Project Summary 
 The Research Education Component (REC) Core will oversee the development and implementation of 
training programs for early-stage investigators that will focus on bridging the gap between preclinical and 
clinical development of therapeutic interventions to prevent, slow, and treat Alzheimer's disease (AD). We will 
leverage rich existing institutional resources, including the Claude D. Pepper Older Americans Independence 
Center, our Clinical and Translational Science Institute (CTSI), and Wake Forest Innovations (liaison with 
industry) to provide a solid, multi-disciplinary infrastructure to support a diverse training curriculum focused on 
translational AD neuroscience research, particularly with regard to the contributory role of metabolic and 
vascular risk factors and disease. We will draw from Wake Forest's extensive scientific community to identify 
mentors, and will recruit early-stage investigators and other trainees from diverse racial and ethnic 
backgrounds through multiple Wake Forest Centers (e.g., ADCC, Sticht Center on Aging, Maya Angelou 
Center for Health Equity, Hypertension and Vascular Research Center, Comparative Medicine/Primate 
Center), and through nearby affiliate academic institutions, including two Historically Black College and 
Universities (HBCUs) with whom we have established collaborative relationships. The REC Core will 
implement an innovative 18-month intensive and tailored training program for junior faculty that includes new 
translational research experiences and targeted mentoring to facilitate transitions from research silos toward 
highly collaborative and interdisciplinary science. The REC will also provide multiple other training 
opportunities for investigators at all levels of career development focused on early transitions from normal 
aging to MCI, and from MCI to AD and other forms of dementia using several platforms (e.g., symposiums, 
seminars, workshops, case conferences, journal clubs). These and other REC Core initiatives will be 
addressed with the following Specific Aims: 1) to expand the career focus of promising junior investigators 
faculty through a new multi-disciplinary Translational Science Mapping Program that will provide individualized 
and targeted mentoring, training, and new research experiences to support the development of combined 
competence in basic science and clinical research, with a focus on translational neuroscience; 2) to support 
research career advancement of junior investigators studying AD or a related topic by providing access to a 
multi-disciplinary curriculum of structured didactic training, which will also focus on strategies to develop 
successful national academic and industry collaborations; 3) to engage trainees from racial and ethnic minority 
backgrounds who are severely underrepresented in AD research; and 4) to evaluate and refine REC Core 
programs using established metrics of academic...

## Key facts

- **NIH application ID:** 9981591
- **Project number:** 5P30AG049638-05
- **Recipient organization:** WAKE FOREST UNIVERSITY HEALTH SCIENCES
- **Principal Investigator:** Laura D. Baker
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $48,119
- **Award type:** 5
- **Project period:** — → 2022-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9981591

## Citation

> US National Institutes of Health, RePORTER application 9981591, Core F: Research Education Component (RL5) (5P30AG049638-05). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/9981591. Licensed CC0.

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