# Bioinformatics (BISR)

> **NIH NIH P30** · UNIVERSITY OF NEBRASKA MEDICAL CENTER · 2020 · $103,288

## Abstract

Project Summary/Abstract: Bioinformatics Shared Resource (BISR) 
Bioinformatics has become an integral part of cancer research due to the high-throughput nature of 
experimental data (broadly dubbed as `omics' data) that are being generated from cancer research projects. 
Thus, a tremendous need exists for developing computational infrastructure for the collection, processing, 
storage, analysis, and facilitation of the use of such data by the cancer research community. The main goals of 
the Bioinformatics Core are to facilitate access to bioinformatics resources and current technology, and to 
provide support and train researchers in the use of computational resources and data analysis tools in 
bioinformatics. The proposed Bioinformatics Core is equipped with locally installed bioinformatics tools and 
databases, licensed software tools (Vector NTI, Ingenuity Pathway Analysis, iPathway, CLC Genomics 
workbench, and Lasergene), dedicated computational servers, data storage with backup options, and access 
to high-end computing servers. The Core offers a wide range of bioinformatic services that fall into five 
thematic areas including (i) analysis of next-generation sequencing (NGS)-based genomics data; (ii) analysis 
of array-based and systems biology data; (iii) use of computer programming, machine-learning, and high- 
performance computing in research projects; (iv) development of software and database applications for 
bioinformatics projects; and (v) scientific consultation. Over the past 4 years, the Core has supported 
numerous research projects at the University of Nebraska Medical Center (UNMC) with over half of the Core 
users hailing from the Buffett Cancer Center. Majority of the Core services used by the Cancer Center 
investigators fall into NGS-based and systems biology related analyses. The Core Director is assisted by four 
well-trained support staff with diverse training backgrounds in computer science, statistics, cancer genomics 
and systems biology. An advisory board that consists of members representing different colleges and schools 
at UNMC oversees the Core. The board reviews the existing services and suggests new services, reviews the 
operating policies and service charges. The Core personnel have been supported by institutional, cancer 
center and other extra-mural grants, which confer stable and sustainable environment to the Core, thus 
facilitates the hiring, training and retaining competent and diverse expertize in the Core that is particularly 
important to the Cancer Center. In addition, the Core Director also leads a research group in cancer genomics 
and bioinformatics and collaborates with a number of cancer center investigators. These collaborations 
facilitate the development of novel and customized data analysis protocols that suit the needs of cancer center 
research projects and create synergistic opportunities to develop interdisciplinary research programs in cancer 
biology.

## Key facts

- **NIH application ID:** 9981645
- **Project number:** 5P30CA036727-34
- **Recipient organization:** UNIVERSITY OF NEBRASKA MEDICAL CENTER
- **Principal Investigator:** CHITTIBABU GUDA
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $103,288
- **Award type:** 5
- **Project period:** 1997-09-05 → 2021-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9981645

## Citation

> US National Institutes of Health, RePORTER application 9981645, Bioinformatics (BISR) (5P30CA036727-34). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/9981645. Licensed CC0.

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