# Biospecimen Core

> **NIH NIH P50** · NORTHWESTERN UNIVERSITY · 2020 · $277,445

## Abstract

BIOSPECIMEN CORE: SUMMARY
The Biospecimen Core is a vital resource that supports all brain tumor research at Northwestern, and is
especially important in seeing that all projects experience clinical translation within the period of SPORE
funding. Regular interactions with the Biostatistics & Bioinformatics Core and Administrative Core will ensure
that each project achieves its objectives, and has positive impact on the care of brain tumor patients.
The Biospecimen Core will have extensive interactions with all projects and cores by acting as the central
repository of patient tissues and renewable tumor resources, by providing the highest quality of tissue
analytical services, and by providing neuropathological consultation. The Director of the Core, Dr. Horbinski, as
well as the Co-Director, Dr. Daniel Brat, will supervise quality control testing of banked specimens, and will
perform all microscopy-based analyses of patient tissues and tumor models for each SPORE project.
Biospecimen Core activities will be performed to accomplish the following aims:
Aim 1: Provide Northwestern brain tumor researchers with annotated biospecimens from brain tumor
patients.
Aim 2: Subject all biospecimens to rigorous quality control.
Aim 3: Propagate, bank, and characterize surgical specimen derivatives, including PDX and cancer
stem cell (CSC) models, to meet ongoing needs for renewable tumor cell sources.
Aim 4: Support SPORE projects with biospecimens and neuropathologic analyses.

## Key facts

- **NIH application ID:** 9981694
- **Project number:** 5P50CA221747-03
- **Recipient organization:** NORTHWESTERN UNIVERSITY
- **Principal Investigator:** Craig Michael Horbinski
- **Activity code:** P50 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $277,445
- **Award type:** 5
- **Project period:** — → —

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9981694

## Citation

> US National Institutes of Health, RePORTER application 9981694, Biospecimen Core (5P50CA221747-03). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/9981694. Licensed CC0.

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