# Population Assessment of Alzheimer's and Related Dementias in Rural Northern Peru

> **NIH NIH R21** · UNIVERSITY OF WASHINGTON · 2020 · $149,111

## Abstract

The overarching goal of this proposed R21 application is to better understand cognitive impairment and dementia
in the LMIC setting of Tumbes, Peru through establishing a baseline of cognitive status for population-based
studies of cognitive impairment and dementia in rural communities. Fifty-nine communities in this region have
participated in prior research conducted by co-investigators on this application. To attain this goal, we propose
the following specific aims: AIM 1: Define the spectrum, type and prevalence of cognitive impairment in Peruvians
60 years of age or older living in rural Northern Peru; AIM 2a: Initiate a population-based cohort of adults with
and without cognitive impairment in rural Latin America to facilitate future longitudinal studies of incidence and
prevention of cognitive decline and dementia; and Aim 2b: Establish a biomarker and biobanking core, containing
information and samples from a large rural population-based cohort of Latin American adults with varying levels
of cognitive impairment. This proposal would establish a new collaboration for population-based and clinical
research in cognitive impairment, dementia and Alzheimer's disease in a well-established research population
in northern Peru with a team of highly experienced investigators in dementia and population health. Although the
research tools proposed for this study are well known, they would provide novel information regarding the
prevalence of dementia and risk factors for cognitive impairment and dementia at a population-level in a unique
rural Latin American population of Northern Peru. We will establish a novel biomarker core in this region with
exciting opportunities for future studies of cognitive decline and dementia. Identification of modifiable risk factors
could provide therapeutic targets and future opportunities to better understand the influence of metabolism upon
cognition over time. In addition, through obtaining information regarding disabilities and quality of life, we will be
able to better characterize the impact of cognitive impairment and dementia upon rural Latin American
communities - information that currently is not available.

## Key facts

- **NIH application ID:** 9982739
- **Project number:** 5R21AG064666-02
- **Recipient organization:** UNIVERSITY OF WASHINGTON
- **Principal Investigator:** Hector Hugo Garcia
- **Activity code:** R21 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $149,111
- **Award type:** 5
- **Project period:** 2019-08-01 → 2024-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9982739

## Citation

> US National Institutes of Health, RePORTER application 9982739, Population Assessment of Alzheimer's and Related Dementias in Rural Northern Peru (5R21AG064666-02). Retrieved via AI Analytics 2026-07-26 from https://api.ai-analytics.org/grant/nih/9982739. Licensed CC0.

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