# Development of Complex Natural Product Libraries and Multidimensional Anticancer Screening Platforms

> **NIH NIH R50** · UNIVERSITY OF FLORIDA · 2020 · $87,938

## Abstract

PROJECT SUMMARY
Natural products chemistry has been an important area of research that fortifies much of the
discovery of modern pharmaceuticals, agrochemicals and veterinary therapeutics. The progress
in natural products has hugely improved modern healthcare and quality of life. The challenge to
make new discoveries and to continually improve and extend the coverage provided by safe,
effective and available therapeutics demand the involvement of specialized expertise in the tools
and methodology of natural products and bio-discovery. With over 18 years of experience in
natural products chemistry dealing with isolation, characterization and biological evaluation of
small molecules from terrestrial plants, micro-organisms, cyanobacteria and eukaryotic algae Dr.
Ratnayake will continue her quest to identify and characterize compounds from natural sources
that promise new advances in pharmacology. She will make use of the infrastructure at the Center
for Natural Products, Drug Discovery and Development (CNPD3) and the UF Health Cancer
Center in a collaborative effort towards finding new therapies and identifying new drug candidates
for cancer treatment, while addressing multiple issues on drug discovery ranging from assay
development, fractionation, isolation, de-replication strategies and screening.

## Key facts

- **NIH application ID:** 9982851
- **Project number:** 5R50CA211487-05
- **Recipient organization:** UNIVERSITY OF FLORIDA
- **Principal Investigator:** Ranjala Ratnayake
- **Activity code:** R50 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $87,938
- **Award type:** 5
- **Project period:** 2016-09-20 → 2022-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9982851

## Citation

> US National Institutes of Health, RePORTER application 9982851, Development of Complex Natural Product Libraries and Multidimensional Anticancer Screening Platforms (5R50CA211487-05). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/9982851. Licensed CC0.

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