# Core C: Kidney Imaging Core

> **NIH NIH P30** · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · 2020 · $87,401

## Abstract

Abstract
The Kidney Imaging Core is an integral part of the Pittsburgh Center for Kidney Research’s mission to support
multidisciplinary and translational research that explores the physiology, pathophysiology, and molecular biology
of the kidney. The Kidney Imaging Core complements each of the other Center cores by providing critical
information about the amounts, localization, and dynamics of molecules, organelles, cells, and tissues in normal
and disease states, and in cell cultures, tissue explants, animal models, and human tissues. The Kidney Imaging
Core, along with the University of Pittsburgh Center for Biological Imaging (CBI), supports subcores that are
dedicated to imaging urinary tract-associated epithelial cells, performing detailed stereology and three-
dimensional tissue and organ reconstruction of the urinary tract, undertaking histopathology studies, and
implementing live-cell/tissue/organ imaging studies. In addition, the Imaging Core provides access to human
kidney tissues through our collaboration with the Center for Critical Care Medicine Tissue Bank. Cutting-edge
imaging resources are available to our users including three-dimensional STED, confocal acquisition using light
sheet illumination, high-speed TIRF, and the newest advances in multiphoton imaging. In addition, the Core
supports freeze-fracture microscopy, all manner of scanning and transmission electron microscopy, and the
latest implementations of tools needed for stereology and histopathology. The Core also provides users with
secondary antibodies and access to our Validated Antibody Collection, which includes a growing number of
antibodies that are carefully screened for specific binding to antigens and can be used to mark selective cell
types in the urinary tract. The aims of the Core are multifold: (1) to serve as a national center for imaging of
kidney- and lower urinary tract-associated cells, tissues, and organs; (2) to support the specialized techniques,
methods, and procedures utilized by the investigators that comprise the Pittsburgh Center for Kidney Research;
(3) to provide for a higher standard of efficiency and quality control through the Core's ability to conduct
procedures on a routine and consistent basis; (4) to transfer Kidney Imaging Core expertise to Center
investigators through training mechanisms including distribution of protocols, hands-on training, and mini
sabbaticals.

## Key facts

- **NIH application ID:** 9983066
- **Project number:** 5P30DK079307-13
- **Recipient organization:** UNIVERSITY OF PITTSBURGH AT PITTSBURGH
- **Principal Investigator:** Gerard L Apodaca
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $87,401
- **Award type:** 5
- **Project period:** — → —

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9983066

## Citation

> US National Institutes of Health, RePORTER application 9983066, Core C: Kidney Imaging Core (5P30DK079307-13). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/9983066. Licensed CC0.

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