# University of Michigan Regional Coordinating Center (RCC) StrokeNet

> **NIH NIH U24** · UNIVERSITY OF MICHIGAN AT ANN ARBOR · 2020 · $308,783

## Abstract

The purpose of a University of Michigan Regional Coordinating Stroke Center (UM RCC) is to continue to
participate fully in the NIH StrokeNet clinical trials network through clinical trial development, enrollment, and
 implementation, and the training of early stage investigators in stroke research. The University of Michigan has
a long track record of clinical science excellence, expertise in clinical stroke management, excellence in
creating stroke systems of care, expertise in stroke clinical trial design and implementation, and a proven
ability to recruit subjects. The UM RCC includes affiliate spokes in a geographically focused region with which
UM has a history of collaboration, and provides access to a large and diverse stroke patient population. UM
has tremendous infrastructure for the conduct of clinical trials including a CTSA-funded Michigan Institute for
Clinical & Health Research, and Clinical Trial Support Units, both of which directly benefit the UM RCC.
Moreover, the Departments of Emergency Medicine and Neurology at UM are fully supportive of the
continuation of a UM RCC. The applicants are part of a dedicated multidisciplinary team of investigators who
are experienced in stroke clinical trials and enthusiastic to continue working collaboratively on Network trials
and offer enrollment to all eligible patients. Also included are world-class experts in stroke basic science who
can continue to contribute to the leadership and training within a UM RCC and the overall network. The UM
RCC has proposed and will continue to propose trials for conduct in the Network. One UM RCC proposed
clinical trial has been approved for funding. The University of Michigan is already home to the NINDS-funded
Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN) National Clinical Coordinating Center
(PI: Barsan) and its prior incarnation, the Neurological Emergencies Treatment Trials (NETT), and thus has
tremendous experience with the design and conduct of clinical trials within networks. Equally as important to
the successful conduct of clinical trials within a UM RCC, the UM Stroke Program has a proven track record for
developing academic clinical researchers in stroke, as this is the primary mission of its fellowship program.
Unique resources are available at UM for formal didactic training in clinical research through its nationally
recognized School of Public Health and its Clinician Scholars Program. Trainees within a UM RCC also benefit
tremendously from the mentorship of a highly integrated multidisciplinary faculty with significant expertise in stroke clinical trials and clinical stroke research. The initial years of the UM RCC have proven its success in
clinical trial enrollment, early investigator training, multi-level network engagement, and clinical trial proposal development.

## Key facts

- **NIH application ID:** 9983183
- **Project number:** 5U24NS107214-03
- **Recipient organization:** UNIVERSITY OF MICHIGAN AT ANN ARBOR
- **Principal Investigator:** DEVIN L BROWN
- **Activity code:** U24 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $308,783
- **Award type:** 5
- **Project period:** 2018-08-15 → 2023-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9983183

## Citation

> US National Institutes of Health, RePORTER application 9983183, University of Michigan Regional Coordinating Center (RCC) StrokeNet (5U24NS107214-03). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/9983183. Licensed CC0.

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